Browsing: Psychopharmacology

The latest news about psychopharmacology and drug research

Ziprasidone and Olanzapine carry no difference in risk of mortality

A study published online this month in the American Journal of Psychiatry in advance of print publication in February 2011 showed no difference in nonsuicide mortality between people taking ziprasidone and another second-generation anti-psychotic in real-world use.

Serotonin uses specialized signaling pathway distinct from pathways used by N-methyltryptamines

Scripps Research Institute scientists have shown for the first time that the neurotransmitter serotonin uses a specialized signaling pathway to mediate biological functions that are distinct from the signaling pathways used by hallucinogenic substances. The new findings could have a profound effect on the development of new therapies for a number of disorders, including schizophrenia and depression.

Just two drinks slow reactions in older people

Blood alcohol levels below the current legal limit for driving have a significant negative effect on a person’s dexterity. Researchers writing in the open access journal BMC Research Notes found that just two single vodka and orange drinks were enough to make senior volunteers struggle at an obstacle avoidance test while walking.

Oxytocin makes people trusting, but not gullible

Oxytocin (OT) is a hormone that plays an important role in social behavior—it has even been nicknamed “the love hormone” and “liquid trust.” Increased levels of OT have been associated with greater caring, generosity, and trust. But does OT increase people’s trust in just anybody or does it act more selectively?

Body clock drugs could ease psychiatric disorders and jet lag

Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC) have successfully used a drug to reset and restart the natural 24 hour body clock of mice in the lab. The ability to do this in a mammal opens up the possibility of dealing with a range of human difficulties including some psychiatric disorders, jet lag and the health impacts of shift work.

Endocannabinoid Blockers Improve Obesity-Related Health Complications

An experimental compound appears to improve metabolic abnormalities associated with obesity, according to a preliminary study led by researchers at the National Institutes of Health. A report of the study, which was conducted with obese mice, appears online today in the Journal of Clinical Investigation.

Study Finds Link Between Estradiol and Depression, Anxiety

A study from the University of Albany found that the administration of the hormone estradiol to aged female mice decreased anxiety-like and depression-like behaviors. This finding may help explain the onset of depression during and after menopause.

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