PsyPost
No Result
View All Result
PsyPost
No Result
View All Result
Home Exclusive Mental Health

Study shows vagus nerve stimulation reduces impairments in stroke patients

by University of Texas at Dallas
December 8, 2015
in Mental Health
Photo credit: kengmerry/Fotolia

Photo credit: kengmerry/Fotolia

Share on FacebookShare on Twitter

A new study involving UT Dallas researchers shows that vagus nerve stimulation (VNS) technology could help improve the lives of hundreds of thousands of people who suffer weakness and paralysis caused by strokes.

The study, published in the journal Stroke, marks the first time that VNS has been tested in individuals recovering from stroke.

VNS already has been approved by the U.S. Food and Drug Administration as a treatment for certain illnesses, such as depression and epilepsy. It involves sending a mild electric pulse through the vagus nerve, which is in the neck. Stimulating this nerve relays information about the state of the body to the brain and encourages it to re-organize in a process called neural plasticity.

The study demonstrated that the VNS experimental treatment is safe in patients recovering from stroke. According to study co-author Dr. Michael Kilgard, professor of neuroscience, it also showed significant potential for reducing impairments among stroke patients.

“This ‘first in humans’ study appears to demonstrate improvement in the recovery that stroke patients make,” Kilgard said. “This was a small study and there is more work to be done, but this is an exciting result.”

According to the American Stroke Association, nearly 800,000 people in the United States are stricken by strokes each year. Eighty percent of stroke survivors are impacted by hemiparesis, a weakness on one side of the body that could last a lifetime. Oral drug therapies have shown little success in reducing impairments and disabilities.

The VNS study included 20 stroke patients who experienced arm weakness due to stroke. The participants were randomly placed into two groups: one with patients who only received rehabilitation therapy, and one with patients who received rehabilitation therapy as well as VNS experimental therapy. The therapy was six weeks long for both groups.

The group that only received rehabilitation improved by an average of three points on the Fugl-Meyer assessment scale (which is used to measure recovery in stroke patients) while the group that received rehabilitation and the VNS experimental treatment improved by an average of nine points.

While specific results varied among the patients, several of those that received VNS reported greater motion and strength in their stroke-affected arms.

“This study demonstrates that vagus nerve stimulation appears to improve the recovery that stroke patients make,” said Kilgard, who is the Margaret Fonde Jonsson Professor at UT Dallas. “VNS is triggered on successful movements to solidify gains that are made during physical therapy.”

The trial occurred in Glasgow, Scotland. But Kilgard said UT Dallas and UT Southwestern Medical Center have opened a new trial that can provide VNS experimental therapy in a trial setting for local stroke patients.

“We are seeking several stroke patients in the Dallas area, each of whom will receive a VNS device as well as physical rehabilitation. We are looking forward to bringing this technology to U.S. patients for the very first time,” he said.

Dr. Robert Rennaker, Texas Instruments Distinguished Chair in Bioengineering, director of the Texas Biomedical Device Center and chairman of the Bioengineering Department was a co-author of the study. He said a key factor in the new study is that it is double-blind, placebo-controlled, and at multiple sites, which is the highest standard for a clinical trial. He said that although it is placebo-controlled, all patients will receive the device and the full therapy.

“We already have seen a number of benefits from vagus nerve stimulation for other conditions,” Rennaker said. “We hope that we ultimately will see such success for stroke patients.”

Dr. Jesse Dawson from the University of Glasgow, Scotland, was the lead author of the study. MicroTransponder, a company that began at UT Dallas, provided funding for the research.

ShareTweetSendScanShareSharePinSend

Get all the latest updates on new psychology research with the free PsyPost app.
 


NEWSLETTER SIGN-UP

STAY CONNECTED

TRENDING

Women who take hormonal contraceptives show superior object memory, study finds

Women’s own body dissatisfaction appears to influence their judgment of other women’s body sizes

Gender-neutral text perceived as less comprehensible than gendered text in Polish, study finds

Shyness linked to reduced behavioral mimicry during conversation via heightened self-focused attention

New psychology research reveals men’s motives for sending unsolicited dick pics

Symptoms of depression decrease with improvements in sense of smell, particularly among patients with dysosmia

RECENT

Women who take hormonal contraceptives show superior object memory, study finds

New psychology research indicates that partisan biases can promote false memories

Gender-neutral text perceived as less comprehensible than gendered text in Polish, study finds

Exercise enhances our enjoyment of music, possibly through increased arousal

Study indicates that thin influencers do not motivate healthy food choices among tweens

  • Cognitive Science
  • COVID-19
  • Mental Health
  • Social Psychology
  • Drug Research
  • Conspiracy Theories
  • Meditation
  • Psychology of Religion
  • Aviation Psychology and Human Factors
  • Relationships and Sexual Health
Powered by

About

PsyPost is a psychology and neuroscience news website dedicated to reporting the latest research on human behavior, cognition, and society. (READ MORE...)

  • Contact us
  • Privacy policy

No Result
View All Result
  • About
    • Newsletter signup form
  • Cart
  • Checkout
  • Contact
  • Contact us
  • My account
  • Privacy policy
  • Psychology news
  • PsyPost app privacy policy
  • Shop
  • SmartMag Home

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

This website uses cookies. By continuing to use this website you are giving consent to cookies being used.