Author European Molecular Biology Laboratory

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Microglia cells prune connections between neurons

Gardeners know that some trees require regular pruning: some of their branches have to be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, discovered. Published online today in Science, the findings could one day help understand neurodevelopmental disorders like autism.