Author Scripps Research Institute

Avatar
Scientists identify mechanism of long-term memory

Using advanced imaging technology, scientists from the Florida campus of The Scripps Research Institute have identified a change in chemical influx into a specific set of neurons in the common fruit fly that is fundamental to long-term memory.

Discrete pathway of the brain governs nicotine addiction

Scientists from the Florida campus of The Scripps Research Institute have identified a pathway in the brain that regulates an individual’s vulnerability to the addictive properties of nicotine. The findings suggest a new target for anti-smoking therapies.

Map of brain connectivity changes during development

Connected highways of nerve cells carry information to and from different areas of the brain and the rest of the nervous system. Scientists are trying to draw a complete atlas of these connections—sometimes referred to as the “connectome”—to gain a better understanding of how the brain functions in health and disease.

New technology can detect molecules specific to Alzheimer’s disease in blood samples

Scientists from the Florida campus of The Scripps Research Institute, have developed a novel technology that is able to detect the presence of immune molecules specific to Alzheimer’s disease in patients’ blood samples. While still preliminary, the findings offer clear proof that this breakthrough technology could be used in the development of biomarkers for a range of human diseases.

Vaccine blocks cocaine high in mice

Researchers from The Scripps Research Institute, Weill Cornell Medical College, and Cornell University have produced a long-lasting anti-cocaine immunity in mice by giving them a unique vaccine that combines bits of the common cold virus with a particle that mimics cocaine.

Scientists report molecular structure of dopamine receptor

A team led by scientists at The Scripps Research Institute has solved the structure of one of the receptors that responds to the neurotransmitter dopamine. Although dopamine transmission is essential to normal brain functioning, the biological assembly of the molecules involved in this crucial neuronal interplay had not been known—until now. The work was reported in the November 19, 2010, issue of the journal Science.

Serotonin uses specialized signaling pathway distinct from pathways used by N-methyltryptamines

Scripps Research Institute scientists have shown for the first time that the neurotransmitter serotonin uses a specialized signaling pathway to mediate biological functions that are distinct from the signaling pathways used by hallucinogenic substances. The new findings could have a profound effect on the development of new therapies for a number of disorders, including schizophrenia and depression.

MeCP2 protein linked to cocaine addiction

Scientists from the Florida campus of The Scripps Research Institute have identified a protein that may act as the trigger controlling the addictive impact of cocaine in the brain. The findings may one day lead to new therapies to treat addiction.

1 5 6 7