Browsing: Psychopharmacology

The latest news about psychopharmacology and drug research

Opioids erase memory traces of pain

A team of researchers at the MedUni Vienna’s Department of Neurophysiology (Centre for Brain Research) has discovered a previously unknown effect of opioids: the study, which has now been published in the highly respected magazine Science and was led by Ruth Drdla-Schutting and Jürgen Sandkühler, shows that opioids not only temporarily relieve pain, but at the right dose can also erase memory traces of pain in the spinal cord and therefore eliminate a key cause of chronic pain.

Scientists confirm tobacco use by ancient Mayans

Archaeologists examining late period Mayan containers have identified nicotine traces from a codex-style flask, revealing the first physical evidence of tobacco use by ancient Mayans.

Study finds superior drug combo for difficult-to-control epilepsy

A combination of two common drugs, lamotrigine and valproate, is more effective in treating difficult-to control epilepsy than other anti-epileptic regimens, according to a University of Washington report to be published online this week in Neurology, the journal of the American Academy of Neurology.

Researcher develops model to foster new drug development to treat pain and epilepsy

Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has been impossible to generate in the laboratory: the conformational changes in voltage-gated sodium channels when they are at rest or actively transmitting a signal in muscle and nerve cells.

Alcohol can lead to unsafe sex: It’s official

A new study has found that alcohol consumption directly impacts a person’s intention to have unsafe sex. In other words, the more you drink, the stronger becomes your intention to engage in unsafe sex.

Neuroscientists boost memory using genetics and new drug

When the activity of a molecule that is normally elevated during viral infections is inhibited in the brain, mice learn and remember better, researchers at Baylor College of Medicine reported in a recent article in the journal Cell.

Drug reverses aging-associated changes in brain cells

Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study in the December 7 issue of The Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.

A more ethical way to compare epilepsy treatments

For the first time, a new research methodology recently approved by the Food and Drug Administration has been used to demonstrate that converting patients from one anti-epileptic drug to another – in this case, lamotrigine extended-release (LTG XR) – is well-tolerated, effective and safe.

Vascular risk linked to long-term antiepileptic drug therapy

New research reveals that patients with epilepsy who were treated for extended periods with older generation antiepileptic drugs (AEDs) may be at increased risk for developing atherosclerosis, a common disorder known as hardening of the arteries.

Scientists discover how to design drugs that could target particular nerve cells

The future of drug design lies in developing therapies that can target specific cellular processes without causing adverse reactions in other areas of the nervous system. Scientists at the Universities of Bristol and Liègein Belgium have discovered how to design drugs to target specific areas of the brain.

Alcohol-related behavior changes: Blame your immune system

When you think about your immune system, you probably think about it fighting off a cold. But new research from the University of Adelaide suggests that immune cells in your brain may contribute to how you respond to alcohol.