A new study found that giving mice 5-MeO-DMT, a short-acting psychedelic, leads to a long-lasting increase of dendritic spine density in the medial frontal cortex region of their brains, potentially countering the neural changes produced by depression. The psychological effects...
New research published in Lancet Public Health reveals that individuals who have experienced higher numbers of adverse childhood experiences are more likely to develop persistent and regular cannabis use patterns during adolescence. The study underscores the crucial link between childhood...
Ketamine tends to increase early life stress-induced aggression in rodent models, but it does not induce significant effects on other behavioral measures related to mood disorders, such as fear memory, anxiety-like behavior, and depression-like behavior, according to new research published...
A recent study published in Frontiers in Psychology explores the potential positive impact of mindfulness meditation and psychedelic use on leadership development among business managers. The research highlights how both practices contribute to enhanced well-being, awareness, creativity, and interpersonal attitudes.
A study conducted using data from the 2020 National Survey on Drug Use and Health has found that individuals reporting serious psychological distress are more likely to be users of cannabis. Both moderate and serious levels of psychological distress were...
Mike Jay's "Psychonauts: Drugs and the Making of the Modern Mind" investigates the history and influence of psychoactive substances, shedding light on how the human relationship with these substances has evolved over time. With a particular focus on the impact...
Cannabis-based medicinal products might help to improve symptom severity, sleep quality, and health-related quality of life in those with anxiety, according to new research published in the journal Psychopharmacology. The findings highlight the need for further research, including randomized controlled...
Psilocybin has antidepressant-like effects and can improve cognitive function in a rat model of depression induced by chronic stress, according to new research published in Psychedelic Medicine. The findings provide new insights into the potential therapeutic applications of psychedelic substances...
Scientists testing coffee against plain caffeine found that plain caffeine only partially reproduces the effects of drinking a cup of coffee, activating areas of the brain that make you feel more alert but not the areas of the brain that...
A new study published in the Journal of Sleep Research has revealed that while veterans might resort to cannabis as a stress relief, it could intensify insomnia symptoms over time. This bidirectional relationship presents a paradox, as what begins as...
New research provides unique insights into how different drugs, including psychedelic substances, engage with the brain's neurotransmitter landscape to produce their effects on brain activity. The findings, published in Science Advances, indicate that psychoactive drugs interact with the brain's neurotransmitter...
An open label study of a group of individuals suffering from posttraumatic stress disorder (PTSD) who also reported suffering chronic pain showed that MDMA-assisted therapy led to significant reduction in pain intensity and pain-related disability in participants with highest levels...
The use of "smart drugs" to enhance productivity in academic and workplace settings is on the rise. A recent study published in Science Advances examined the effects of three popular smart drugs – methylphenidate, modafinil, and dextroamphetamine – on real-life...
A study published in the Journal of Affective Disorders reveals that psilocybin-assisted therapy reduces experiential avoidance, leading to improved well-being and decreased depression, anxiety, and suicidal thoughts in depressed patients. The research highlights the significance of experiential avoidance as a...
A recent study explored deep brain stimulation (DBS ) as a potential treatment for alcohol use disorder. The findings suggest that DBS may help reduce symptoms related to alcohol use disorder, such as increased abstinence, reduced cravings, and decreased anhedonia....