Alzheimer's Disease

New research using UK Biobank data suggests that people with a higher genetic risk for Alzheimer’s disease may actually report less social isolation and stronger family relationships in midlife, challenging the idea that risk for dementia always reduces social connection.

A new study pinpoints where and when the earliest signs of Alzheimer’s disease begin. Researchers discovered a marker for brain inflammation rises in a specific memory-related brain region, coinciding precisely with the appearance of the disease’s first toxic plaques.

For the first time, researchers have directly linked air pollution to the physical hallmarks of Alzheimer’s disease in human brain tissue. An autopsy study found individuals from more polluted areas had significantly more amyloid plaques and tau tangles, worsening their...

Scientists have developed a rapid brainwave test that may detect memory impairment associated with Alzheimer’s disease in just minutes. The Fastball EEG test could help identify people in need of further screening before more serious symptoms emerge.

New research from Harvard suggests that lithium—a mineral best known for batteries and mood stabilizers—might protect the brain from Alzheimer’s disease. Low lithium levels appear to trigger the toxic buildup of proteins linked to memory loss and cognitive decline.

Scientists have identified a promising non-drug method for reversing key cellular features of Alzheimer’s disease. In lab-grown neurons, a combination of vitamin B3 and a green tea antioxidant restored energy levels and jumpstarted the cell’s ability to remove toxic protein...

A year-long study suggests vortioxetine may offer greater improvements in both cognition and mood for people with Alzheimer’s disease and depression compared to other antidepressants, potentially making it a promising treatment option alongside standard Alzheimer’s therapies.

Scientists have discovered that excess sugar stored in brain cells may worsen Alzheimer’s disease. Clearing this buildup in lab models reduced cell damage and extended lifespan, pointing to a surprising new target for slowing or preventing dementia.

What if a protein we thought caused dementia is actually essential for building a healthy brain? New research shows a key Alzheimer's protein is abundant in newborns, flipping our understanding of the disease and its biological triggers on its head.

In a large longitudinal study, researchers identified apathy as the most consistent predictor of functional decline in people with Alzheimer’s disease, suggesting that this often-overlooked symptom may play a more central role in disease progression than previously recognized.

Older adults who ate more than one egg per week had a lower risk of developing Alzheimer’s dementia and showed fewer Alzheimer’s-related brain changes. About 39% of this association was explained by higher dietary choline intake from eggs.

Researchers identified four common disease pathways—centered on mental health, brain disorders, cognitive decline, and vascular issues—that often precede Alzheimer’s, showing that the sequence of conditions may better predict risk than individual diagnoses alone.

Smaller, shallow brain folds in the posteromedial cortex show greater thinning with age and Alzheimer’s disease, and their structure is closely linked to memory and executive function, suggesting they may be key markers of cognitive decline.

Spending less time in slow wave and REM sleep may accelerate brain atrophy in regions affected early in Alzheimer’s disease, according to new research. The findings support sleep quality as a potential factor in preserving brain health.