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(R)-ketamine restores neuronal activity in the anterior insular cortex and improves social memory in mice affected by chronic social isolation, according to new research.
A single dose of the antidepressant citalopram reduces neural responses to internal bodily sensations, particularly during anxiety, revealing serotonin's role in modulating interoception.
Caffeine may worsen brain grey matter loss during sleep deprivation, potentially hindering recovery and exacerbating the negative effects of chronic sleep restriction, new research reveals.
Adolescent alcohol use is linked to larger hippocampal volumes, while tobacco and cannabis show no such effect, revealing substance-specific impacts on brain development.
Cannabis terpenes effectively reduce chronic neuropathic pain, matching morphine's efficacy, and enhance pain relief when combined with morphine without increasing side effects or addiction risk.
Older adults attending psychedelic retreats reported significant well-being improvements, driven by social connections and group activities, despite experiencing less intense immediate psychedelic effects compared to younger participants.
A new study has found that coffee consumption is heritable, with specific genes influencing how much coffee people drink and its association with other substance use behaviors.
Neuroimaging research has found that psilocybin increases self-inhibition in visual brain regions and enhances top-down connectivity, leading to vivid, internally generated visual imagery with eyes closed.
Recent research found that cannabidiol reduces cocaine preference in mice and restores gut microbiota diversity disrupted by cocaine, suggesting CBD's potential in treating cocaine addiction.
Cannabis users exhibit weaker neural responses in brain regions related to cognitive flexibility during task-switching, despite showing no significant differences in task performance compared to nonusers.
In recent years, the resurgence of interest in psychedelic substances has spotlighted psilocybin as a potential breakthrough in mental health treatment.
Psilocybin significantly reduced the frequency and severity of cluster headaches, with participants experiencing approximately a 50% decrease in weekly attacks and improvements in pain severity and medication use.
Researchers found that adolescent binge drinking of alcohol mixed with energy drinks temporarily boosted neural function in rats but led to long-term reductions in hippocampal synaptic plasticity
Researchers observed a 1250% increase in microdosing-related Google searches from 2015 to 2023, coinciding with the loosening of cannabis and psychedelic regulations, with over three million searches in 2023 alone.
People who use psychedelics tend to have higher levels of BDNF, a brain protein that promotes neuroplasticity and neuron growth, suggesting potential mental health benefits.