Dementia

New research shows that untreated sleep-disordered breathing alters the brain physically. These disruptions may make the brain more vulnerable to Alzheimer’s disease, fundamentally changing how toxic proteins build up across different stages of cognitive decline.

A recent study using advanced cell mapping shows that lithium chloride changes the activity of multiple enzymes linked to Alzheimer’s disease. These findings could help researchers design safer, more effective treatments for cognitive decline and dementia.

A massive review of over four million people suggests that better cardiovascular fitness protects the mind. Published in Nature Mental Health, the research links higher physical fitness levels to a lower risk of depression and dementia.

While statins are highly effective at protecting against heart attacks and strokes, a massive new medical records study reveals that the popular cholesterol-lowering medications do not offer additional protection against Alzheimer's disease or other age-related dementias.

Older adults who suddenly develop feelings of loneliness experience an accelerated decline in their memory and thinking skills. A new longitudinal study tracks how cognitive decline speeds up immediately following the onset of social isolation.

Standard cognitive tests can be flawed by cultural and educational biases. Researchers argue that monitoring a patient's ability to perform daily routines offers a more practical, culturally adaptable early warning system for dementia.

A specific measurement of body shape called the Body Roundness Index provides evidence of a strong link between excess belly fat and depression in people with dementia. This simple metric outperforms traditional methods like body mass index.

A nationwide study of Finnish medical records reveals that severe infections are an independent risk factor for dementia, elevating patients' longer-term risk regardless of other underlying health problems.

Researchers used a microscopic model of human nerves and muscles to show that Alzheimer's disease directly damages peripheral nerves. This physical damage happens independently of cognitive decline and does not improve with standard medications for the illness.

Alzheimer’s disease pathology begins early in a tiny brain region called the locus coeruleus. Emerging research suggests that stimulating the vagus nerve could help regulate this critical area, potentially preventing memory loss and early cognitive aging.

While dementia is commonly associated solely with memory loss, it is actually an umbrella term for over 100 conditions. Understanding rare subtypes—which can affect vision, movement, and behavior—is crucial for early diagnosis and specialized care.

Older adults diagnosed with depression face a severe risk of cognitive decline. A new longitudinal study reveals that depressed elderly individuals are nearly five times more likely to develop Alzheimer’s disease than their non-depressed peers.

Older adults carrying a genetic variation linked to Alzheimer's disease might protect their brain health by eating more meat. A recent study suggests personalized diets based on genetics could help prevent dementia in this large population.

A recent study provides evidence that access to high-speed rail networks can improve cognitive health in older adults. The infrastructure appears to boost mental well-being by reducing air pollution, easing depression, and increasing economic opportunities.

Changing the types of fat in your diet might help preserve cognitive health as you age. A new cohort study links substituting saturated animal fats with plant-based vegetable oils to a lower risk of developing dementia.