Dementia

Alzheimer's disease and frontotemporal dementia share overlapping symptoms, making early diagnosis difficult. A new study reveals that tiny brain-derived vesicles carry distinct genetic markers for each condition, offering a potential new avenue for early detection.

A new study suggests that regular treadmill running can fully reverse memory loss and reduce toxic brain plaques in mice with Alzheimer’s disease. The benefits appear linked to a specific cellular pathway that boosts brain health.

A new study reveals that two different inflammatory proteins in the blood signal separate types of brain damage. Both distinct pathways ultimately converge to fuel Alzheimer's-related tau tangles, brain shrinkage, and memory decline in older adults.

A new study reveals that older adults with stiffer arteries face a significantly higher risk of developing dementia. Researchers suggest that monitoring arterial stiffness could eventually become a valuable tool for predicting and managing cognitive decline.

A decades-long study of British adults suggests that enduring economic strain across adulthood correlates with lower midlife cognitive scores and increased brain atrophy in later years.

A large study of older adults in China suggests that depression can lead to a decline in memory and thinking skills by causing people to withdraw from their social circles, highlighting a potential pathway to protect aging brains.

Professions requiring constant spatial navigation physically reshape the hippocampus, the brain region Alzheimer’s attacks first. By routinely building mental maps, individuals may develop a cognitive reserve that delays the onset of severe memory loss.

New research reveals that physical social isolation harms the aging brain independently of subjective feelings of loneliness. Simulated public health interventions show that reconnecting isolated older adults can directly protect against cognitive decline.

A recent meta-analysis indicates that the four most common forms of dementia feature distinct immune system responses. These biological differences occur independently of other health conditions and might eventually guide targeted treatments for cognitive decline.

A 12-week program requiring older adults to read out loud, write by hand, and solve basic math problems for 30 minutes a day resulted in measurable improvements on cognitive tests.

People with Down syndrome face an elevated risk of developing Alzheimer's disease. A recent study indicates that simple blood tests can accurately detect early brain changes, paving the way for easier diagnosis and inclusive clinical trials.

A recent review in Molecular and Cellular Neuroscience suggests that popular weight-loss and diabetes drugs might help clear brain proteins associated with Alzheimer's disease. While animal studies show promise, human data remains limited.

High levels of a specific blood protein during midlife suggest an increased risk for vascular dementia. Researchers found evidence that this protein might alter immune activity and contribute to the gradual loss of healthy brain tissue.

A new scientific review suggests that polyphenols—natural compounds found in berries, tea, and olive oil—may help protect the brain from age-related decline. However, researchers emphasize eating whole foods over relying on high-dose supplements.