Alzheimer's Disease

Researchers used a microscopic model of human nerves and muscles to show that Alzheimer's disease directly damages peripheral nerves. This physical damage happens independently of cognitive decline and does not improve with standard medications for the illness.

Alzheimer’s disease pathology begins early in a tiny brain region called the locus coeruleus. Emerging research suggests that stimulating the vagus nerve could help regulate this critical area, potentially preventing memory loss and early cognitive aging.

Older adults diagnosed with depression face a severe risk of cognitive decline. A new longitudinal study reveals that depressed elderly individuals are nearly five times more likely to develop Alzheimer’s disease than their non-depressed peers.

Older adults carrying a genetic variation linked to Alzheimer's disease might protect their brain health by eating more meat. A recent study suggests personalized diets based on genetics could help prevent dementia in this large population.

A recent study shows that combining magnetic brain scans with computer models can safely measure how dementia medications affect living human brains. This approach could replace invasive tests and speed up the development of new treatments for Alzheimer's disease.

A recent study shows that accessible blood tests can accurately identify Alzheimer’s disease. When combined with standard cognitive assessments, these tools offer a reliable diagnostic approach for historically underrepresented populations in Latin America.

Researchers have developed a diagnostic panel that identifies cognitive decline by analyzing how blood proteins fold. This method accurately distinguishes between healthy aging and Alzheimer's disease, offering a fresh tool for early detection.

Older adults with exceptional memories continue to grow new brain cells. A recent study published in the journal Nature shows that this biological process nearly stops in people with Alzheimer's disease.

A new study reveals how a liver enzyme shores up the blood-brain barrier. Blocking a specific vessel protein replicated the cognitive benefits of exercise in aging mice and Alzheimer’s models.

New research reveals that repetitive strings of the amino acid serine can kill brain cells and accelerate the formation of toxic tau tangles associated with Alzheimer’s disease.

A genetic screen of human neurons has identified a protein complex that tags toxic tau for destruction. The findings explain why some brain cells are resilient to Alzheimer’s disease while others succumb to degeneration.

Scientists have found a way to jumpstart the brain's waste-disposal system. By inhibiting a common metabolic enzyme, researchers enabled immune cells to devour Alzheimer’s plaque and improve cognitive function in mouse models.

A promising Alzheimer’s blood test requires different interpretation for men and women, according to a new study. Researchers found that at identical protein levels, men experience more severe cognitive decline and brain damage than their female counterparts.

A new study in mice suggests that tumors may inadvertently protect against Alzheimer’s. Researchers found that cancers release a protein called cystatin-C, which crosses the blood-brain barrier to clear toxic amyloid plaques.

A new study suggests a compound in cannabis could protect the brain from Alzheimer’s disease. Researchers found that treating rats with cannabidiol prevented memory loss and inflammation by activating specific brain receptors.