Alzheimer's Disease

A new study in rats shows that while high-fat and high-sugar diets both impair memory, only sugar triggers the accumulation of Alzheimer’s-associated proteins within the energy centers of brain cells.

A new study suggests repurposing existing cancer drugs could offer a potent treatment for Alzheimer’s. The combination therapy, tested in mice, works by correcting gene expression errors across both neurons and support cells.

The popular metabolic drug semaglutide failed to preserve memory in patients with early Alzheimer’s disease. New data shows the treatment did not slow cognitive decline compared to a placebo, despite influencing disease-related biology.

A new study suggests that brain communication networks are less stable in individuals with Alzheimer’s. This increased “neural flexibility,” particularly in the visual system, may help predict which individuals will transition to dementia.

Loss of the "push-pull" relationship between the brain's default mode and attention networks is a robust sign of Alzheimer's. New data shows this predicts decline independently of education or protein tangles.

The olfactory system offers a direct pathway to the brain's memory and emotion centers. Now, scientists find this connection may also serve as a crucial diagnostic window into long-term neurological health, preceding traditional clinical symptoms.

A recent paper details a new mechanism for protecting the brain from Alzheimer's-related damage. The research shows how the metabolite NAD+ helps repair cellular function and improve memory.

New research reveals how Alzheimer's disease extends beyond the brain, potentially disrupting the body's energy management system.

A study of dolphins stranded in Florida suggests that repeated exposure to algal toxins may trigger brain changes associated with Alzheimer’s disease.

An individual's genetic tendency for elevated levels of a key protein in the blood signal a heightened risk for developing Alzheimer's disease, according to new research.

A new study offers a surprising look at the link between physical activity and the proteins that build up in the brains of people with Alzheimer's disease.

Women are more often diagnosed with Alzheimer’s disease, but why? New research challenges a common assumption about brain aging, pointing scientists toward other potential explanations for this well-known disparity.

A novel treatment for Alzheimer's doesn't attack brain plaques directly. Instead, it repairs a critical protective barrier, leading to remarkable recovery in animal models and offering a new direction for future therapies.

Inhaled CBD reduced inflammation and improved cognition in mice with Alzheimer’s, according to a study in eNeuro, pointing to a promising immune-based approach for treating the disease beyond traditional amyloid-focused therapies.

New research suggests that higher iron levels in specific brain regions may help identify who is at risk for developing memory problems years before symptoms emerge. The findings may offer a new way to track Alzheimer’s risk using MRI scans.