Alzheimer's Disease

New research reveals that repetitive strings of the amino acid serine can kill brain cells and accelerate the formation of toxic tau tangles associated with Alzheimer’s disease.

A genetic screen of human neurons has identified a protein complex that tags toxic tau for destruction. The findings explain why some brain cells are resilient to Alzheimer’s disease while others succumb to degeneration.

Scientists have found a way to jumpstart the brain's waste-disposal system. By inhibiting a common metabolic enzyme, researchers enabled immune cells to devour Alzheimer’s plaque and improve cognitive function in mouse models.

A promising Alzheimer’s blood test requires different interpretation for men and women, according to a new study. Researchers found that at identical protein levels, men experience more severe cognitive decline and brain damage than their female counterparts.

A new study in mice suggests that tumors may inadvertently protect against Alzheimer’s. Researchers found that cancers release a protein called cystatin-C, which crosses the blood-brain barrier to clear toxic amyloid plaques.

A new study suggests a compound in cannabis could protect the brain from Alzheimer’s disease. Researchers found that treating rats with cannabidiol prevented memory loss and inflammation by activating specific brain receptors.

A new study uses magnetic stimulation to show that brain complexity drops in early Alzheimer’s disease. The findings suggest the condition may be fundamentally linked to a breakdown in the neural networks supporting consciousness.

A new study finds that a signaling pathway is hyperactive in female brains with Alzheimer's, halting the production of new neurons. Blocking this pathway successfully restored regeneration in mice.

The specific way you breathe during meditation may determine its impact on Alzheimer's risk factors. A recent clinical trial found that slow breathing reduces amyloid beta peptides, while mindfulness with normal breathing tends to increase them.

Why does running help the brain? New research using single-cell sequencing highlights specific genetic pathways restored by exercise.

A study in Cell Reports Medicine shows that restoring metabolic balance can reverse advanced Alzheimer’s in mice. These results suggest that the brain can repair itself to achieve full neurological recovery.

New findings suggest cannabis microdosing protects cognition in mild Alzheimer’s cases without the side effects of recreational use.

A new analysis reveals that Alzheimer’s disrupts mitochondrial function and insulin signaling more severely in women than men. The study suggests female brains may attempt unique biological compensations to fight the disease’s progression.

Researchers have preserved memory in mice by triggering support cells to remove amyloid deposits. The findings suggest that enhancing the brain’s natural cleaning system could offer a new therapeutic path for neurodegenerative conditions.

The Alzheimer’s therapy Lecanemab appears to recruit the brain’s immune system. New findings in Nature Neuroscience suggests the drug uses its Fc region to trigger microglia into removing amyloid plaques.