Depression

A new study finds that a supervised Nordic walking program can significantly reduce moderate to severe depression symptoms in just five weeks. The aerobic workout proved especially beneficial for participants who started with the most severe symptoms.

Physical exercise is known to improve mental health. A new study reveals that a muscle-released protein called apelin travels to the brain during exercise, promoting neuron growth and alleviating depression.

A new longitudinal study reveals that specific brain wave patterns emerging around age nine can reliably predict whether a child will develop anxiety or depression during their teenage years, opening the door for proactive mental health interventions.

A recent study in The Journal of Clinical Psychiatry suggests that a single dose of psilocybin, paired with psychological support, may rapidly and safely reduce chronic suicidal thoughts in adults with severe, treatment-resistant depression.

People with depression often describe feeling stuck. Now, researchers have found a physical basis for this sensation, mapping an altered energy landscape that traps the brain in maladaptive loops and restricts cognitive flexibility.

A new study reveals that white blood cells in people with depression show abnormal activity in genes usually associated with brain connections. The findings highlight depression as a whole-body condition, potentially paving the way for future blood-based diagnostics.

A new pilot study suggests that combining the psychedelic compound psilocybin with cognitive behavioral therapy is well-tolerated and highly effective at reducing symptoms of clinical depression. Researchers observed profound improvements in patients' moods and emotional regulation.

A new analysis shows both antidepressants and short-term psychodynamic therapy effectively treat depression. However, for patients starting with highly severe symptoms, medication might offer slightly better improvements than therapy alone.

Rising rates of teenage depression are often blamed on growing income inequality. However, a decade-long study of over half a million adolescents reveals that local shifts in the wealth gap have practically zero impact on teen depressive symptoms.

A recent study suggests the brains of teenage girls with depression fail to adapt to repeated social rejection. This lack of habituation in the amygdala provides evidence for disrupted social learning during a sensitive developmental period.

New research shows that older adults who get high-quality rest are much less likely to develop depression symptoms over a multi-year period. Improving your daily sleeping habits might offer a powerful way to protect your long-term mental health.

A new machine learning analysis reveals how childhood trauma can amplify genetic vulnerabilities to depression, uncovering thousands of biological interactions that traditional statistical methods have consistently missed.

A recent clinical trial suggests that treating the immune system with an anti-inflammatory drug could relieve symptoms in people with difficult-to-treat depression. The research provides early evidence that lowering inflammation tends to improve mood, fatigue, and anxiety.

Why do dementia and depression look so similar in older adults? New research maps the brain's chemistry to show how the two conditions share serotonin disruptions but diverge sharply in how they alter or destroy brain cells.

A nationwide survey reveals that eating meals at irregular times is tied to a higher likelihood of depression. Dietary diversity can cushion this effect, while regularly skipping breakfast amplifies the connection between sporadic eating schedules and low mood.