Depression

New research highlights how two distinct styles of meditation reduce symptoms of depression. While focused-attention practices and introspective self-inquiry operate through slightly different mental pathways, both help individuals detach from negative thoughts and perceived threats.

In recent FDA Phase 2 trials, a single dose of the experimental psychedelic luvesilocin eliminated postpartum depression symptoms in 71% of patients within seven days. The breakthrough medication will enter Phase 3 trials by late 2026.

A large international twin study reveals that childhood economic inequality shapes adult mental health. Published in Psychological Medicine, the research provides evidence that a wide wealth gap can magnify a person's genetic risk for developing depression.

Young adults who struggle to feel pleasure often misjudge the physical exertion required for rewards. A new computational study reveals how specific learning deficits might lead them to pass up high-value opportunities in daily life.

Deep brain stimulation offers hope for severe depression, but how it works has remained a mystery. A new study reveals the therapy actually physically reshapes the brain’s white matter pathways, explaining its long-lasting mood-boosting effects.

Researchers tracked over 300 young adults for a month to see how depression symptoms interact. They discovered that specific feelings, like anhedonia and sadness, act as central hubs that are strongly linked to a wider array of mental and physical...

A new study finds that a supervised Nordic walking program can significantly reduce moderate to severe depression symptoms in just five weeks. The aerobic workout proved especially beneficial for participants who started with the most severe symptoms.

Physical exercise is known to improve mental health. A new study reveals that a muscle-released protein called apelin travels to the brain during exercise, promoting neuron growth and alleviating depression.

A new longitudinal study reveals that specific brain wave patterns emerging around age nine can reliably predict whether a child will develop anxiety or depression during their teenage years, opening the door for proactive mental health interventions.

A recent study in The Journal of Clinical Psychiatry suggests that a single dose of psilocybin, paired with psychological support, may rapidly and safely reduce chronic suicidal thoughts in adults with severe, treatment-resistant depression.

People with depression often describe feeling stuck. Now, researchers have found a physical basis for this sensation, mapping an altered energy landscape that traps the brain in maladaptive loops and restricts cognitive flexibility.

A new study reveals that white blood cells in people with depression show abnormal activity in genes usually associated with brain connections. The findings highlight depression as a whole-body condition, potentially paving the way for future blood-based diagnostics.

A new pilot study suggests that combining the psychedelic compound psilocybin with cognitive behavioral therapy is well-tolerated and highly effective at reducing symptoms of clinical depression. Researchers observed profound improvements in patients' moods and emotional regulation.

A new analysis shows both antidepressants and short-term psychodynamic therapy effectively treat depression. However, for patients starting with highly severe symptoms, medication might offer slightly better improvements than therapy alone.