New research shows that microglia—the brain’s immune cells—respond more strongly to alcohol in people with a high genetic risk for alcohol use disorder. The findings offer insight into how inherited factors can shape brain responses to alcohol exposure.
Read moreDetailsThe length of your fingers might predict how much alcohol you drink, according to a new study linking prenatal hormone exposure to alcohol use in university students.
Read moreDetailsA small clinical trial finds semaglutide may help people with alcohol use disorder cut back on drinking and reduce cravings.
Read moreDetailsDrinking alcohol in social settings is often more enjoyable, and new research explains why: the positive effects of alcohol are actually amplified when your conversation partner is also under the influence.
Read moreDetailsA new study in PNAS Nexus reveals that communities experiencing mass shootings see sustained increases in alcohol sales.
Read moreDetailsA study found that individuals with alcohol use disorder show reduced gray matter in cortical and limbic areas. These brain changes correlate with increased anxiety, depression, and memory deficits.
Read moreDetailsNew research highlights a potential mechanism behind intoxicated aggression.
Read moreDetailsThe use of diabetes drugs semaglutide and liraglutide was associated with fewer hospitalizations for alcohol use disorder compared to approved treatments, suggesting these medications may have potential benefits for managing alcohol-related health issues.
Read moreDetailsResearchers found increased thalamus-insula connectivity in individuals with alcohol use disorder during unpredictable threats, linked to higher alcohol intake. This suggests heightened threat reactivity may drive excessive drinking.
Read moreDetailsA new study has uncovered a critical molecular mechanism behind alcohol's effects on the brain. Researchers found that a previously uncharacterized protein, TMEM132B, amplifies alcohol's influence on GABAA receptors.
Read moreDetailsAlzheimer’s disease and alcohol use disorder share similar gene expression changes, including increased inflammation, disrupted brain signaling, and vascular damage, suggesting alcohol use may worsen or accelerate Alzheimer’s progression through shared molecular mechanisms.
Read moreDetailsTeen binge drinking disrupts brain development, affecting white and grey matter, functional connectivity, and neurodevelopmental processes like myelination.
Read moreDetailsHangxiety, or hangover anxiety, is the intense worry or dread some people feel after drinking alcohol. It stems from brain chemical imbalances, dehydration, or regret over actions while intoxicated, and is worsened by pre-existing anxiety or heavy drinking.
Read moreDetailsChronic consumption of high-alcohol beer in rodents disrupted sperm production by increasing oxidative stress, reducing cyclin D1 expression, and elevating p21 levels, leading to impaired cell division and structural damage in testicular tissue.
Read moreDetailsHigh school IQ predicts midlife drinking habits: smarter teens are more likely to drink moderately or heavily as adults but binge less often, with income partially explaining the link between intelligence and alcohol use.
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