New research finds that individuals with midlife occupations demanding high cognitive engagement have a lower risk of developing mild cognitive impairment and dementia after age 70 compared to those in more routine, less cognitively demanding jobs.
Both alcohol consumption and stress exposure throughout life significantly heighten the risk of developing Alzheimer's disease and other dementias, through mechanisms that likely involve neuroinflammation affecting key brain regions.
A new study has discovered that metabolites from gut bacteria interact with specific human receptors, potentially influencing Alzheimer's disease. These findings could lead to novel therapies targeting these interactions, offering hope for treating or even preventing the disease.
Recent research suggests that not all stressful life events impact Alzheimer's risk equally. Events in childhood and midlife are particularly influential, potentially triggering long-term brain changes and inflammation.
A recent study suggests that higher cognitive abilities in adolescence are linked to a reduced risk of developing dementia 60 years later. Education plays a key role in this relationship, potentially mitigating dementia risks through more complex careers and lifelong...
A study suggests a smartphone app could accurately detect mild cognitive impairment, a precursor to Alzheimer's disease, through unsupervised memory tests. This approach could significantly enhance early diagnosis and monitoring of Alzheimer’s, making it more accessible and frequent.
Scientists developed a human neuron model to explore tau protein spread in neurodegenerative diseases, identifying the UFMylation cascade as a novel therapeutic target and uncovering about 500 genes influencing tau propagation.
A UK study found individuals with behavioral variant frontotemporal dementia who had musical experience showed better social and emotional functioning. This suggests that music might play a role in enhancing socio-emotional well-being in dementia patients.
Researchers found that brains have grown larger over recent decades, with those born in the 1970s having significantly bigger brain volumes and surface areas compared to those born in the 1930s.
Mild cognitive impairment – an early stage of dementia – is widely underdiagnosed in people 65 and older.
A decade-long U.S. study found a slight increase in dementia risk among people exposed to PM2.5 air pollution, particularly from agriculture and wildfires. The research emphasizes the need for targeted air quality interventions to reduce dementia's burden.
A study revealed that a blood test, identifying 11 proteins, can predict dementia with 90% accuracy up to 15 years before diagnosis, offering a non-invasive, cost-effective alternative for early detection and intervention, enhancing patient care and treatment opportunities.
A new study in Neurology shows erectile dysfunction medications may reduce Alzheimer's risk by 18%. Exploring drug repurposing, researchers found men prescribed these drugs had a lower incidence of Alzheimer's, offering a promising avenue for prevention and highlighting the need...
A recent study in the Neurobiology of Aging reveals that individuals with high levels of openness, a trait marked by curiosity and a broad interest spectrum, have a stronger cognitive reserve, potentially shielding against the cognitive decline seen in conditions...
New research has linked a healthier diet to a reduced risk of dementia and a deceleration in the pace of aging. This study, published in the Annals of Neurology, provides new insights into how diet can influence the complex mechanisms...