Neuroscience reveals the brain disconnect behind music anhedonia

When I ask a lecture theatre full of students how they would feel if they could never listen to a piece of music again, most are horrified. Many have been plugged into their headphones until the moment the class begins. But without fail, one or two will shyly admit that their lives would not change at all if music didn’t exist.

Psychologists call this “music anhedonia”, meaning an absence of pleasure for music. And a new paper from neuroscientists in Spain and Canada suggests it is caused by a problem with communication between different parts of the brain.

For many of us, apathy towards music seems unfathomable. Yet, for 5%-10% of the population, this is their norm.

I see it often in my own research and practice in people with memory loss, where I ask people to select favourite songs as a way of accessing significant memories.

It has always fascinated me that some people look at me blankly and say, “I’ve never been that bothered by music”. It is such a contrast to the majority who love to talk about their first record, or the tune played at their wedding.

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Recent evidence shows considerable variation in the depth of people’s emotional response to music. Around 25% of the population are hyperhedonic, which is an almost obsessive urge to engage intensely and frequently with music.

Research in this field typically uses the Barcelona Music Reward Questionnaire (BMRQ), which asks people about the significance of music in daily life: how often they listen to records, whether they hum along, and if there are songs that give them a shiver down the spine.

Low scorers are classified as having music anhedonia and many researchers further verify this in the lab by measuring heart rate, sweat response and breathing while music is playing. For most of us, these physiological markers change dramatically during emotional songs. But in those with music anhedonia, there are often no physiological effects at all.

One theory is that reduced enjoyment for music may reflect a more generalised anhedonia, an absence of pleasure for anything. Often, this is linked to disruption to the reward pathways in the brain, in areas such as the nucleus accumbens, orbitofrontal cortex and insula.

It is a common feature of depression, which, along with other mood disorders, can correlate with a lack of response to music . However, this does not explain specific music anhedonia, where people happily enjoy other rewards such as food, socialising and films, but remain indifferent to music.

An alternative possibility is that people with reduced interest in music simply don’t understand it, perhaps due to difficulties with processing melody and harmony. To test this, we can look at people with amusia – a deficit in music perception, which affects the ability to identify familiar tunes or detect wrong notes. This occurs when there is reduced activity in key regions in the frontotemporal cortex in the brain, which handles complex processing of pitch and melody. However, some people with the condition have an extreme and obsessional love of music.

In any case, other research shows that those with music anhedonia often have normal musical perception, with no problem recognising songs or distinguishing major from minor chords.

So, what is going on? The new paper provides a detailed analysis of all the research in this field to date. The researchers explain that while the brain networks underlying music perception and reward are both intact in people with music anhedonia, the communication between them is severely disrupted. There is little to no traffic between the auditory processing parts of the brain and the reward centre.

People with typical responses to music have significant activity in this pathway, which is higher for pleasant music than for neutral sounds. A 2018 study showed that you can increase music-induced pleasure by artificially stimulating these communication tracts using magnetic pulses.

The new analysis may give scientists insights into clinical conditions where everyday rewards seem to be reduced or enhanced, for example eating disorders, sex addictions and gambling problems.

These findings also challenge the common assumption that everyone loves music. Most people do, but not all, and the variation comes down to differences in the wiring of the brain. Sometimes it follows brain injury, but more often people are born this way, and a March 2025 study found evidence of a genetic link.

Music is everywhere – in shops, gyms, restaurants, healthcare settings – and it can be incredibly powerful. But perhaps we should resist the urge to see it as a panacea and respect the fact that for some, silence is golden.

This article is republished from The Conversation under a Creative Commons license. Read the original article.