Researchers found that ketamine increases redundant brain activity, especially in the alpha frequency band, leading to dissociative experiences. Portable EEG devices effectively tracked these changes, offering insights into how ketamine alters brain function during rest and tasks.
New research explores how music could influence patient experiences during intranasal ketamine therapy for treatment-resistant depression, potentially opening doors to more effective and comfortable treatment protocols.
New research explores an unexpected effect of ketamine on individuals with treatment-resistant depression, revealing potential implications for its use beyond traditional antidepressant applications.
(R)-ketamine restores neuronal activity in the anterior insular cortex and improves social memory in mice affected by chronic social isolation, according to new research.
A new study has found no significant link between participation in ketamine clinical trials and subsequent symptoms of ketamine abuse.
A study found ketamine's rapid antidepressant effects in rats hinge on activating the brain's opioid system, particularly β-endorphin in the prefrontal cortex. Blocking this pathway negates ketamine's benefits, unveiling potential targets for new depression treatments.
Northwestern University researchers have uncovered how ketamine delivers rapid and prolonged depression relief by activating new neurons for immediate effects and increasing their production for lasting benefits. This breakthrough could lead to safer, ketamine-inspired antidepressants.
SSRIs like escitalopram may boost brain plasticity, potentially aiding in depression treatment by enhancing neural adaptability and communication. Novel treatments like intranasal esketamine and psychedelics target different brain receptors, suggesting diverse mechanisms of action. Understanding these processes is crucial for...
A multi-center U.S. study suggests ketamine significantly improves severe, treatment-resistant depression, offering hope for rapid, effective therapy.
The drug ketamine can reduce the symptoms of post-traumatic stress disorder, or PTSD, and symptoms of depression in patients as early as a day after injection.
Scientists have discovered that rapid-acting antidepressants like ketamine, psilocybin, and scopolamine can alter negative mood biases in rodent models, a symptom common in depressive disorders. This breakthrough, published in Science Translational Medicine, suggests new approaches to treat Major Depressive Disorder...
A new study suggests that ketamine significantly improves depression and anhedonia symptoms by altering brain connectivity in the anterior cingulate cortex, specifically influencing different subregions linked to mood regulation and reward processing. The findings have been published in Translational Psychiatry.
A new study shows how depression alters brain connectivity, particularly in the habenula, and how ketamine treatment reverses these changes. This research enhances understanding of depression and ketamine's rapid antidepressant effects.
A new study shows that chronic ketamine exposure causes major changes in mice brains, particularly in the dopamine system, which is crucial for mood and motivation. The study, published in Cell Reports, highlights ketamine's complex effects on brain regions, indicating...
A study of individuals with treatment-resistant depression found that four infusions of the antidepressant ketamine led to enhanced cognitive functioning that persisted for five weeks. These improvements appeared to be independent of the antidepressant response. The study was published in...