Ketamine

A new study shows that chronic ketamine exposure causes major changes in mice brains, particularly in the dopamine system, which is crucial for mood and motivation. The study, published in Cell Reports, highlights ketamine's complex effects on brain regions, indicating...

A study of individuals with treatment-resistant depression found that four infusions of the antidepressant ketamine led to enhanced cognitive functioning that persisted for five weeks. These improvements appeared to be independent of the antidepressant response. The study was published in...

A recent meta-analysis published in the Journal of Psychopharmacology indicates that subanesthetic doses of ketamine may provide rapid and sustained relief from anxiety, with effects noticeable within a few hours and lasting up to two weeks. However, the researchers stress...

Ketamine tends to increase early life stress-induced aggression in rodent models, but it does not induce significant effects on other behavioral measures related to mood disorders, such as fear memory, anxiety-like behavior, and depression-like behavior, according to new research published...

A recent study found that the antidepressant effects of intravenous ketamine treatment are linked to rapid changes in neuroplasticity. The study analyzed data from depressed individuals who received ketamine or a placebo, revealing that increased neuroplasticity in specific brain regions...

A recent study found that ketamine infusion therapy was associated with a significant reduction in self-reported symptoms of anxiety, depression, and suicidality, with stable effects observed during the maintenance phase. The study, published in the Journal of Affective Disorders, provides...

New research provides evidence that ketamine therapy might be a suitable option for adults with borderline personality disorder and treatment-resistant depression. The new findings have been published in Psychiatry Research.