Alzheimer's Disease

An examination of genetic data from the UK Biobank reveals that individuals with a higher genetically estimated lean body mass (i.e., the mass of muscles, bones, and non-fat tissues) exhibit a lower likelihood of contracting Alzheimer’s disease. Additionally, those with...

New research published in BMC Medicine suggests that deep sleep, also known as non-REM slow-wave sleep, could help protect against memory loss in older adults with a high burden of Alzheimer's disease. The study found that deep sleep acts as...

Practicing paced breathing exercises appears to have an impact on the levels of peptides associated with Alzheimer's disease, according to new research published in Scientific Reports. The findings suggest that such interventions may have potential in modulating biomarkers related to...

Damage to mitochondria (the energy-producing structures within cells) could actually be the cause of Alzheimer’s. Despite increasing evidence showing mitochondrial loss in the neurons of patients with Alzheimer’s, the idea that mitochondrial dysfunction could be a cause has remained on...

A study of oceanic dolphins found stranded (and dead) on shores of Scotland showed evidence of pathological changes in their brains that correspond to Alzheimer’s disease in humans. Analyses revealed that all examined cetaceans accumulated amyloid plaque pathology in their...

New research provides evidence that some types of natural environments are associated with a decreased risk hospitalization for neurological diseases such as Alzheimer's disease and Parkinson's disease. The findings have been published in JAMA Network Open.

An analysis of 22 large-scale gene expression datasets pointed to exercise and activity in general as the most effective theoretical treatment for reversing gene expressions typical of Alzheimer’s disease. Fluoxetine, a well-known antidepressant sold often commercially as Prozac or Zoloft,...

A new study published to Frontiers is the first to identify formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease, potentially paving the way for inexpensive and convenient disease screening.  

Noradrenergic drugs target the noradrenergic system, which comprises a small part of the brainstem called the locus coeruleus. This area is involved in a broad array of brain functions, such as memory, attention and learning. This system is primarily controlled...

When the disease is well reproduced by the model, researchers can assume that a treatment that works on it will be likely to work in people with the disease. Cell cultures and organoids from patients are particularly promising because of...

Drinking coffee may reduce your risk of Alzheimer’s disease, according to findings published in the journal Frontiers in Aging Neuroscience. The study followed a sample of older adults for 10 years and found that those who consumed more coffee showed slower...

A good night’s sleep has always been linked to better mood, and better health. Now, scientists have even more evidence of just how much sleep – and more specifically our circadian rhythm, which regulates our sleep cycle – is linked...

Beta-amyloid and tau are two proteins that serve useful functions in the brain, but in Alzheimer’s disease – the most common form of dementia – they go rogue and destroy brain cells (neurons). This happens when beta-amyloid forms clumps on...

Since the human genome was first mapped, scientists have discovered hundreds of genes influencing illnesses like breast cancer, heart disease and Alzheimer’s disease. Unfortunately, Black people, Indigenous people and other people of color are underrepresented in most genetic studies. This...

A recent study appearing in the Journal of Neuroinflammation has brought further clarity to the role of astrocytes in the beneficial effects of voluntary exercise on patients with Alzheimer’s disease. The effects of increased, voluntary physical exercise on cognitive functions...