Alzheimer's Disease

An analysis of 22 large-scale gene expression datasets pointed to exercise and activity in general as the most effective theoretical treatment for reversing gene expressions typical of Alzheimer’s disease. Fluoxetine, a well-known antidepressant sold often commercially as Prozac or Zoloft,...

A new study published to Frontiers is the first to identify formic acid as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease, potentially paving the way for inexpensive and convenient disease screening.  

Noradrenergic drugs target the noradrenergic system, which comprises a small part of the brainstem called the locus coeruleus. This area is involved in a broad array of brain functions, such as memory, attention and learning. This system is primarily controlled...

When the disease is well reproduced by the model, researchers can assume that a treatment that works on it will be likely to work in people with the disease. Cell cultures and organoids from patients are particularly promising because of...

Drinking coffee may reduce your risk of Alzheimer’s disease, according to findings published in the journal Frontiers in Aging Neuroscience. The study followed a sample of older adults for 10 years and found that those who consumed more coffee showed slower...

A good night’s sleep has always been linked to better mood, and better health. Now, scientists have even more evidence of just how much sleep – and more specifically our circadian rhythm, which regulates our sleep cycle – is linked...

Beta-amyloid and tau are two proteins that serve useful functions in the brain, but in Alzheimer’s disease – the most common form of dementia – they go rogue and destroy brain cells (neurons). This happens when beta-amyloid forms clumps on...

Since the human genome was first mapped, scientists have discovered hundreds of genes influencing illnesses like breast cancer, heart disease and Alzheimer’s disease. Unfortunately, Black people, Indigenous people and other people of color are underrepresented in most genetic studies. This...

A recent study appearing in the Journal of Neuroinflammation has brought further clarity to the role of astrocytes in the beneficial effects of voluntary exercise on patients with Alzheimer’s disease. The effects of increased, voluntary physical exercise on cognitive functions...

Genetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a common feature of cardiovascular disease, according to a new study by an international team of researchers led by scientists at UC...

More than 30m people worldwide suffer from Alzheimer’s disease – the most common form of dementia. Unfortunately, there is no cure, only drugs to ease the symptoms. However, my latest review, suggests a way to treat the disease. I found...

A new study of Alzheimer's disease by Fiona Kerr and Linda Partridge at University College London, uses mouse and fruit fly models to show that Keap1, which inhibits the protective protein Nrf2, is a promising target for new preventative drugs...