Subscribe
The latest psychology and neuroscience discoveries.
My Account
  • Mental Health
  • Social Psychology
  • Cognitive Science
  • Neuroscience
  • About
No Result
View All Result
PsyPost
PsyPost
No Result
View All Result
Home Exclusive Psychopharmacology Psychedelic Drugs

Scientists dive deep into Reddit data to decode the mysterious familiarity experienced in DMT trips

by Eric W. Dolan
September 21, 2023
in Psychedelic Drugs
Share on TwitterShare on Facebook

Imagine a substance that can transport your mind to a realm of unimaginable familiarity, even if you’ve never been there before. A recent study, published in the Journal of Psychoactive Drugs, delves into the mysterious world of DMT (dimethyltryptamine) experiences reported on Reddit. Researchers sought to understand the profound sense of familiarity that some users encounter during DMT-induced experiences and the potential implications of this enigmatic phenomenon.

DMT is a naturally occurring psychedelic compound found in various plants and animals. It is known for inducing intense, short-lived altered states of consciousness when consumed. Users commonly describe encounters with entities, otherworldly landscapes, and a profound sense of insight. While DMT has intrigued scientists, its effects remain enigmatic, and little is known about why some users experience this deep familiarity.

The authors behind the new study were particularly captivated by the reports of familiarity in DMT experiences. They set out to explore this phenomenon in depth, driven by curiosity about its nature and potential implications.

“The DMT experience is fundamentally non-ordinary and bizarre but can still enduringly impact beliefs concerning the nature of reality and ontological worldviews,” explained study author David Lawrence (@davidwlawrence1), an assistant professor at the University of Toronto and medical director of the David L. MacIntosh Sport Medicine Clinic. “It’s both paradoxical and intriguing that some individuals report a sense of familiarity during a DMT journey, despite its otherworldly nature. This particular aspect has not been previously explored in a dedicated study and we felt it warranted more attention.”

To conduct their investigation, the researchers employed a mixed-methods qualitative analysis of DMT experiences posted on Reddit between 2009 and 2018. They began by manually screening the titles of over 30,000 posts, narrowing down to 3,778 unique experiences. Within this subset, they identified 227 instances that mentioned a sense of familiarity. Among these, 56 were from users trying DMT for the first time, classifying them as “DMT-naïve.”

The research team then conducted a grounded theory inductive qualitative analysis, identifying meaningful units related to familiarity within these 227 experiences. Additional themes associated with the DMT experience were also documented, using established questionnaires like the Mystical Experience Questionnaire (MEQ) and the Ego Dissolution Inventory (EDI). This comprehensive approach allowed the researchers to gain deeper insights into the sense of familiarity reported by DMT users.

The study revealed that 24.7% of the DMT experiences involving familiarity were from first-time users, dispelling the notion that prior psychedelic exposure was responsible for this sensation.

“Interestingly, none of these experiences attributed the sense of familiarity to prior psychedelic or DMT experiences,” Lawrence noted. “This was an important step to further our understanding the phenomenological feature.”

Google News Preferences Add PsyPost to your preferred sources

Despite the intense familiarity, these DMT experiences often coexisted with non-ordinary states of consciousness, such as mysticism, transcendence of space and time, ineffability, and ego dissolution. In essence, the sense of familiarity was not tied to typical, everyday experiences but rather existed in parallel with these extraordinary phenomena.

To better understand this intriguing phenomenon, the researchers developed the Sense of Familiarity Questionnaire (SOF-Q). This 19-item questionnaire, organized into five thematic categories, aimed to capture the various facets of DMT-induced familiarity. It covered areas like the familiarity with emotions, places, the act of going through the experience, transcendent features, and familiarity imparted by entity encounters.

Using an exploratory Bayesian latent class analysis, the researchers identified two distinct classes of individuals within the study sample who shared similar responses to the SOF-Q items. Class 2, comprising most participants (76%), displayed a response pattern suggesting a strong sense of familiarity related to many aspects of the DMT experience. Class 1, representing approximately one-quarter of participants (24%), showed a slightly different pattern.

“Using the newly introduced Sense of Familiarity Questionnaire (SOF-Q), we were able to identify distinct participant groups based on their experiences, especially around entity encounters and emotions,” Lawrence explained. “This unique sense of familiarity during DMT experiences presents an enigma that paves the way for future research into this captivating phenomenon.”

Both Class 1 and Class 2 participants had similar responses in terms of the place, space, state, environment, the act of going through the experience, and transcendent features during their DMT trips, but Class 1 participants stood out by reporting a greater sense of familiarity when it came to encounters with entities and the feelings, emotions, or knowledge they acquired during their experiences.

“The finding that some participants felt familiarity imparted by an ‘entity encounter’ is surprising,” Lawrence told PsyPost. “Encountering seemingly autonomous sentient beings during DMT experiences is a widely reported phenomenon, but the aspect of these entities conveying a sense of familiarity adds depth to the intrigue surrounding such encounters.”

“I would encourage readers to delve into the source material and explore the quoted passages firsthand. The veridicality of the sense of familiarity not-withstanding, the passion and conviction expressed by some individuals were truly remarkable.”

For example, one DMT user wrote: “Before I knew it, I was in a seemingly infinite emerald fractal forest. As I was examining the landscape around me, from out of the shadows of the trees and bushes stepped these little forest sprites. They welcomed me with open arms saying, ‘Why have you been away so long?’ The feeling I got from these beings was that they were ancestral. They knew me and I knew them, and I just hadn’t seen them in ages.”

This study has shed light on the elusive nature of familiarity during DMT experiences. Importantly, it debunked the notion that prior exposure to DMT or other psychedelics triggers this sensation. Instead, familiarity appears to be a unique aspect of DMT journeys, coexisting with profound alterations in consciousness.

While the exact mechanisms behind DMT-induced familiarity remain uncertain, the researchers offered some intriguing possibilities. The brain’s medial temporal lobe (MTL) is known to play a role in memory processes, and the amygdala is associated with familiarity. However, DMT seems to induce familiarity without recollection, challenging conventional memory models.

The study’s findings also align with the concept of the brain entering a highly flexible state under the influence of psychedelics, known as the Relaxed Beliefs Under Psychedelics (REBUS) model. As the acute effects of DMT subside, the brain returns to a state reminiscent of previous encounters, potentially triggering a sense of familiarity.

Although this study offers valuable insights, it’s important to note its limitations. The findings are based on self-reported experiences shared on Reddit, which may not fully represent the diversity of DMT users. Additionally, the study’s correlational nature means causality cannot be inferred, and further research is needed to validate these findings.

“Given this is the first study into this phenomenon, future prospective controlled studies are needed to validate the findings,” Lawrence said.

Future research may explore the role of endogenous DMT in consciousness and compare the phenomenological features of DMT experiences with non-substance induced states of consciousness. This could help unravel the mystery of DMT-induced familiarity and its implications for our understanding of consciousness and memory.

The study, “N, N-Dimethyltryptamine (DMT)-Occasioned Familiarity and the Sense of Familiarity Questionnaire (SOF-Q)“, was authored by David Wyndham Lawrence, Alex P DiBattista, and Christopher Timmermann.

Previous Post

Differing commitment levels in romantic relationships may not forecast breakup, study finds

Next Post

Depressed individuals have reduced connectivity in brain regions responsible for cognitive functioning

RELATED

Republican lawmakers lead the trend of using insults to chase media attention instead of policy wins
Psychedelic Drugs

Can psychedelics help trauma survivors reconnect intimately?

April 16, 2026
Little-known psychedelic drug reduces motivation to take heroin in rats, study finds
Anxiety

Researchers find DMT provides longer-lasting antidepressant effects than S-ketamine in animal models

April 15, 2026
Antidepressants may diminish psilocybin’s effects even after discontinuation
Depression

Psychedelic therapy and traditional antidepressants show similar results under open-label conditions

April 14, 2026
Study finds microdosing LSD is not effective in reducing ADHD symptoms
Depression

Low doses of LSD alter emotional brain responses in people with mild depression

April 12, 2026
Casual sex is linked to lower self-esteem and weaker moral orientations in women but not men
Early Life Adversity and Childhood Maltreatment

Psychedelic retreats linked to mental health improvements in people with severe childhood trauma

April 9, 2026
Does psilocybin really provide long-term relief from depression, as new study suggests?
Psilocybin

Psilocybin slows down human reaction times and impairs executive function during the acute phase of use

April 5, 2026
Psychedelic experiences linked to long-term improvements in psychological flexibility, study finds
Psilocybin

Can a psychedelic journey change what you value most?

April 4, 2026
Lifting weights can slow down biological brain aging in older adults
Ayahuasca

Short-acting psychedelic DMT shows promise as a rapid treatment for major depressive disorder

March 31, 2026

STAY CONNECTED

RSS Psychology of Selling

  • Why personalized ads sometimes backfire: A research review explains when tailoring messages works and when it doesn’t
  • The common advice to avoid high customer expectations may not be backed by evidence
  • Personality-matched persuasion works better, but mismatched messages can backfire
  • When happy customers and happy employees don’t add up: How investor signals have shifted in the social media age
  • Correcting fake news about brands does not backfire, five-study experiment finds

LATEST

Can a common parasite medication calm the brain’s stress circuitry during alcohol withdrawal?

Childhood trauma and attachment styles show nuanced links to alternative sexual preferences

New study reveals how political bias conditions the impact of conspiracy thinking

Cognition might emerge from embodied “grip” with the world rather than abstract mental processes

Men and women show different relative cognitive strengths across their lifespans

Early exposure to forever chemicals linked to altered brain genes and impulsive behavior in rats

Soft brain implants outperform rigid silicon in long-term safety study

Disclosing autism to AI chatbots prompts overly cautious, stereotypical advice

PsyPost is a psychology and neuroscience news website dedicated to reporting the latest research on human behavior, cognition, and society. (READ MORE...)

  • Mental Health
  • Neuroimaging
  • Personality Psychology
  • Social Psychology
  • Artificial Intelligence
  • Cognitive Science
  • Psychopharmacology
  • Contact us
  • Disclaimer
  • Privacy policy
  • Terms and conditions
  • Do not sell my personal information

(c) PsyPost Media Inc

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

Subscribe
  • My Account
  • Cognitive Science Research
  • Mental Health Research
  • Social Psychology Research
  • Drug Research
  • Relationship Research
  • About PsyPost
  • Contact
  • Privacy Policy

(c) PsyPost Media Inc