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Home Exclusive Neuroimaging

New research maps how the brain processes different aspects of life satisfaction

by Karina Petrova
December 13, 2025
in Neuroimaging
[Adobe Stock]

[Adobe Stock]

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A new study suggests that the brain uses distinct neural pathways to process different aspects of personal well-being. The research indicates that evaluating family relationships activates specific memory-related brain regions, while assessing how one handles stress engages areas responsible for cognitive control. These findings were published recently in the journal Emotion.

Psychologists and neuroscientists have struggled to define exactly what constitutes a sense of well-being. Historically, many experts viewed well-being as a single, general concept. It was often equated simply with happiness or life satisfaction. This approach assumes that feeling good about life is a uniform experience. However, more recent scholarship argues that well-being is multidimensional. It is likely composed of various distinct facets that contribute to overall mental health.

To understand how we can improve mental health, it is necessary to identify the mechanisms behind these different components. A team of researchers set out to map the brain activity associated with specific types of life satisfaction. The study was conducted by Kayla H. Green, Suzanne van de Groep, Renske van der Cruijsen, Esther A. H. Warnert, and Eveline A. Crone. These scientists are affiliated with Erasmus University Rotterdam and Radboud University in the Netherlands.

The researchers based their work on the idea that young adults face unique challenges in the modern world. They utilized a measurement tool called the Multidimensional Well-being in Youth Scale. This scale was previously developed in collaboration with panels of young people. It divides well-being into five specific domains.

The first domain is family relationships. The second is the ability to deal with stress. The third domain covers self-confidence. The fourth involves having impact, purpose, and meaning in life. The final domain is the feeling of being loved, appreciated, and respected. The researchers hypothesized that the brain would respond differently depending on which of these domains a person was considering.

To test this hypothesis, the team recruited 34 young adults. The participants ranged in age from 20 to 25 years old. This age group is often referred to as emerging adulthood. It is a period characterized by identity exploration and significant life changes. The researchers used functional magnetic resonance imaging, or fMRI, to observe brain activity. This technology tracks blood flow to different parts of the brain to determine which areas are working hardest at any given moment.

While inside the MRI scanner, the participants completed a specific self-evaluation task. They viewed a series of sentences related to the five domains of well-being. For example, a statement might ask them to evaluate if they accept themselves for who they are. The participants rated how much the statement applied to them on a scale of one to four.

The task did not stop at a simple evaluation of the present. After rating their current feelings, the participants answered a follow-up question. They rated the extent to which they wanted that specific aspect of their life to change in the future. This allowed the researchers to measure both current satisfaction and the desire for personal growth.

In addition to the brain scans, the participants completed standardized surveys outside of the scanner. One survey measured symptoms of depression. Another survey assessed symptoms of burnout. The researchers also asked about feelings of uncertainty regarding the future. These measures helped the team connect the immediate brain responses to the participants’ broader mental health.

The behavioral results from the study showed clear patterns in how young adults view their lives. The participants gave the lowest positivity ratings to the domain of dealing with stress. This suggests that managing stress is a primary struggle for this demographic. Consequently, the participants reported the highest desire for future change in this same domain.

The researchers analyzed the relationship between these ratings and the mental health surveys. They found that higher positivity ratings in all five domains were associated with fewer burnout symptoms. This means that feeling good about any area of life may offer some protection against burnout.

A different pattern emerged regarding the desire for change. Participants who reported more burnout symptoms expressed a stronger desire to change how they felt about having an impact. They also wanted to change their levels of self-confidence and their feelings of being loved. This suggests that burnout is not just about exhaustion. It is also linked to a desire to alter one’s sense of purpose and social connection.

Depressive symptoms showed a broad association with the desire for change. Higher levels of depression were linked to a wish for future changes in almost every domain. The only exception was self-confidence. This implies that young adults with depressive symptoms are generally unsatisfied with their external circumstances and relationships.

The brain imaging data revealed that the mind does indeed separate these domains. When participants evaluated sentences about positive family relationships, a specific region called the precuneus became highly active. The precuneus is located in the parietal lobe of the brain. It is known to play a role in thinking about oneself and recalling personal memories.

This finding aligns with previous research on social cognition. Thinking about family likely requires accessing autobiographical memories. It involves reflecting on one’s history with close relatives. The activity in the precuneus suggests that family well-being is deeply rooted in memory and self-referential thought.

A completely different neural pattern appeared when participants thought about dealing with stress. For these items, the researchers observed increased activity in the dorsolateral prefrontal cortex. This region is located near the front of the brain. It is widely recognized as a center for executive function.

The dorsolateral prefrontal cortex helps regulate emotions and manage cognitive control. Its involvement suggests that thinking about stress is an active cognitive process. It is not just a passive feeling. Instead, it requires the brain to engage in appraisal and regulation. This makes sense given that the participants also expressed the greatest desire to change how they handle stress.

The study did not find distinct, unique neural patterns for the other three domains. Self-confidence, having impact, and feeling loved did not activate specific regions to the exclusion of others. They likely rely on more general networks that overlap with other types of thinking.

However, the distinction between family and stress is notable. It provides physical evidence that well-being is not a single state of mind. The brain recruits different resources depending on whether a person is focusing on their social roots or their emotional management.

The researchers also noted a general pattern involving the medial prefrontal cortex. This area was active during the instruction phase of the task. It was also active when participants considered their desire for future changes. This region is often associated with thinking about the future and self-improvement.

There are limitations to this study that should be considered. The final sample size included only 34 participants. This is a relatively small number for an fMRI study. Small groups can make it difficult to detect subtle effects or generalize the findings to the entire population.

The researchers also noted that the number of trials for each condition was limited. Participants only saw a few sentences for each of the five domains. A higher number of trials would provide more data points for analysis. This would increase the statistical reliability of the results.

Additionally, the study design was correlational. This means the researchers can see that certain brain patterns and survey answers go together. However, they cannot say for certain that one causes the other. For instance, it is not clear if desiring change leads to burnout, or if burnout leads to a desire for change.

Future research could address these issues by recruiting larger and more diverse groups of people. It would be beneficial to include individuals from different cultural backgrounds. Different cultures may prioritize family or stress management differently. This could lead to different patterns of brain activity.

Longitudinal studies would also be a logical next step. Following participants over several years would allow scientists to see how these brain patterns develop. It is possible that the neural correlates of well-being shift as young adults mature into their thirties and forties.

Despite these caveats, the study offers a new perspective on mental health. It supports the idea that well-being is a multifaceted construct. By treating well-being as a collection of specific domains, clinicians may be better able to help patients.

The study, “Neural Correlates of Well-Being in Young Adults,” was authored by Kayla H. Green, Suzanne van de Groep, Renske van der Cruijsen, Esther A. H. Warnert, and Eveline A. Crone.

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