Psychedelic Drugs

A study of a large, nationally representative sample of U.S. adults has revealed that those who reported lifetime use of ecstasy (i.e., using ecstasy at least once in their life) were less likely to report having difficulty dealing with strangers,...

A study of U.S. Special Operations Forces Veterans participating in an ibogaine and 5-MeO-DMT treatment in Mexico showed that participants treated with these psychedelic substances showed a significant reduction in alcohol misuse 1 month after the start of the treatment....

A recent study published in the Journal of Psychopharmacology found that for those who had used psychedelics in the past, even one dose can result in lasting belief changes about the supernatural or non-physical world.  Specifically, the findings revealed significant...

A new experiment in Japan showed that when mice are exposed to a chronic social defeat stress condition, they develop a number of adverse health conditions. But these adverse health conditions were absent in mice that were repeatedly injected with...

The practice of "microdosing" appears to result in a decrease in emotional diversity, according to new research published in the Journal of Psychedelic Studies.

The results from the first randomized, double-blind, placebo-controlled study to systematically investigate the effects of psilocybin in cluster headache has been published in the scientific journal Headache. The initial study provides useful information for creating bigger and more conclusive studies...

The use of psilocybin, a hallucinogenic substance found in some "magic" mushrooms, has stronger connection to how people feel about nature compared to the use of other psychedelic drugs, according to new research published in the Journal of Psychopharmacology.

Many doctors treat depression with SSRIs, but could psychedelic medication be more effective? A study published in BJ Psych Open suggests that psilocybin, a psychedelic substance found in "magic" mushrooms, may be more beneficial than certain antidepressants for helping improve...

A new online survey of U.S. adults indicates that people who report using any of the classic psychedelics at least once in their lives also reported smoking cigarettes less often and eating healthier diets. The study was published in Therapeutic...

A new study published in the Journal of Psychopharmacology is the first to characterize the psychological impacts of psilocybin among people with bipolar disorder. The findings indicate that many people with bipolar disorder who consume psilocybin, the primary psychoactive component...

New research has found that race and ethnicity moderate the associations between the use of psychedelic drugs and major depressive episodes in a large, nationally representative sample of U.S. adults. The findings have been published in the Journal of Psychopharmacology.

Researchers in the United Kingdom studied whether the effects of psilocybin, a naturally occurring hallucinogenic drug, depend on the body mass index of the person, thereby requiring higher doses for the same effect in heavier people. The results showed that...

A recent study published in the New England Journal of Medicine suggests that psilocybin therapy may offer therapeutic benefits for patients with treatment-resistant depression. When administered alongside psychological support, a 25 mg psilocybin dose reduced depression scores among treatment-resistant patients. However,...

Simple computer exercises using positive words and images designed to boost self-worth can prolong the antidepressant effects of ketamine in people with depression.