Psilocybin

Psilocybin-assisted therapy has shown promise as a treatment for depression. New research published in Cannabis finds that cannabis users expected that cannabis-assisted therapy could produce similar subjective experiences and have similar therapeutic benefits for the treatment of depression as psilocybin-assisted...

An analysis of a large international drug survey suggests that psilocybin is a relatively safe drug, with only 0.2% of magic mushroom users having sought emergency medical care after use. The findings, published in the Journal of Psychopharmacology, further suggest that such...

People with depressive symptoms appear to think it is relatively important that guides for psilocybin-assisted psychotherapy have personally used the psychedelic substance themselves, according to a new study published in the Journal of Psychoactive Drugs.

Opioid abuse is a prevalent and very dangerous substance use disorder. Psychedelic use has been proposed as a treatment for various substance use disorders, leading people to question if it would be an effective treatment for opioid abuse. A study...

Psilocybin is the primary mind-altering substance in psychedelic “magic” mushrooms. Preliminary research has indicated that combining psilocybin with supportive psychotherapy can result in lasting improvements in patients with major depressive disorder and the findings have resulted in glowing media coverage....

The psychedelic substance psilocybin causes transient changes to the sleep-wake architecture of laboratory mice, according to new preliminary research published in Translational Psychiatry. The findings provide new details about how the drug impacts sleep-related brain activity.

The use of psilocybin -- the active component of "magic" mushrooms -- is associated with a decreased likelihood of engaging in criminal behavior, according to new research. The findings have been published in the Journal of Psychopharmacology.

Consuming small doses of psilocybin at regular intervals -- a process known as microdosing -- does not appear to improve symptoms of depression or anxiety, according to new research published in the Journal of Psychopharmacology. The placebo-controlled study casts doubt...

Recent findings published in the journal ACS Pharmacology & Translational Science suggest that psilocybin, in conjunction with psychotherapy, reduces suicidal ideation and loss of meaning among patients with life-threatening cancer. These mental health improvements were maintained months to years following treatment. Cancer...

Psilocybin-assisted psychotherapy appears to increase both cognitive and neural flexibility in patients with major depressive disorder, according to new research published in Translational Psychiatry. But the findings suggest that psychedelic-induced increases in neural flexibility do not always result in cognitive...

Scientists have begun to examine whether the psychedelic drug psilocybin, the active component of "magic" mushrooms, can help people who feel insecure in their attachments to others. Their preliminary research, published in ACS Pharmacology & Translational Science, suggests that psilocybin-assisted...

People who use mental health services in Ireland generally have a favorable view of psychedelic research, according to a new study published in the Irish Journal of Medical Science. A little over half of those surveyed said they would be...

A new double-blind, placebo-controlled neuroimaging study sheds light on how psilocybin alters the way in which the brain processes tactile sensations and mental representations of one's body. The findings have been published in Cerebral Cortex. Psilocybin, the active component in...

Yale scientists have found that a single dose of psilocybin given to mice induces a rapid and long-lasting increase in connections between pyramidal neurons in the medial frontal cortex, an area of the brain known to be involved in control...

Low doses of psilocybin and ketamine can heighten food-related motivation and improve attention in poorly-performing male rats, according to new research published in Frontiers in Pharmacology. The new findings shed light on some of the potential benefits of microdosing, which...