Psilocybin

A study published in the Journal of Affective Disorders reveals that psilocybin-assisted therapy reduces experiential avoidance, leading to improved well-being and decreased depression, anxiety, and suicidal thoughts in depressed patients. The research highlights the significance of experiential avoidance as a...

A new study suggests that psilocybin-assisted group therapy is a promising approach for cancer patients dealing with depressive symptoms. The research, which appears in the Journal of Pain and Symptom Management, provides initial evidence of the safety, feasibility, and possible...

Incorporating the psychedelic drug psilocybin into psychotherapy shows promise in the treatment of depression, according to new research published in the Journal of Psychopharmacology. But the study also highlights the difficulty of implementing effective blinding procedures to prevent expectancy effects...

A new study suggests that the use of certain antidepressants, specifically SSRIs and SNRIs, may weaken the acute subjective effects of psilocybin in some individuals. The findings, which appear in the Journal of Psychopharmacology, indicate that this dampening effect on...

Blocking the subjective psychedelic effects of psilocybin does not appear to interfere with the substance's ability to potentially help with obsessive behaviors, according to new research published in Translational Psychiatry. The findings contribute to the growing body of research on...

New research published in iScience provides unique insights into how psilocybin alters brain activity during psychedelic experiences. The findings suggest that while the overall activity of the brain becomes more chaotic during the psychedelic state, the brain's ability to maintain...

People who use psychedelic substances in an attempt to self-treat their mental health tend to report mild-to-moderate positive outcomes, according to new research published in the Journal of Psychopharmacology. But there were more negative effects reported by these individuals than...

The results from the first randomized, double-blind, placebo-controlled study to systematically investigate the effects of psilocybin in cluster headache has been published in the scientific journal Headache. The initial study provides useful information for creating bigger and more conclusive studies...

The use of psilocybin, a hallucinogenic substance found in some "magic" mushrooms, has stronger connection to how people feel about nature compared to the use of other psychedelic drugs, according to new research published in the Journal of Psychopharmacology.

Many doctors treat depression with SSRIs, but could psychedelic medication be more effective? A study published in BJ Psych Open suggests that psilocybin, a psychedelic substance found in "magic" mushrooms, may be more beneficial than certain antidepressants for helping improve...

A new study published in the Journal of Psychopharmacology is the first to characterize the psychological impacts of psilocybin among people with bipolar disorder. The findings indicate that many people with bipolar disorder who consume psilocybin, the primary psychoactive component...

Researchers in the United Kingdom studied whether the effects of psilocybin, a naturally occurring hallucinogenic drug, depend on the body mass index of the person, thereby requiring higher doses for the same effect in heavier people. The results showed that...

A recent study published in the New England Journal of Medicine suggests that psilocybin therapy may offer therapeutic benefits for patients with treatment-resistant depression. When administered alongside psychological support, a 25 mg psilocybin dose reduced depression scores among treatment-resistant patients. However,...