Alzheimer's Disease

Combining Alzheimer's drugs Donepezil and Memantine significantly extends patients' lives, offering new hope for improved treatment and survival.

Researchers discovered a genetic variant that reduces Alzheimer's disease risk by up to 70%, aiding in the removal of toxic amyloid from the brain. This highlights the role of the brain's blood vessels and suggests new therapeutic approaches.

Researchers have discovered that the brain protein Mfsd7c plays a crucial role in exporting excess choline, challenging previous beliefs and opening new possibilities for treating Alzheimer’s disease and age-related cognitive decline.

Researchers found that reduced connectivity between the locus coeruleus and medial temporal lobe in cognitively healthy individuals is linked to faster brain atrophy and cognitive decline, particularly in the presence of amyloid beta, suggesting early markers for Alzheimer's disease progression.

A high-fat diet leads to metabolic deterioration and significant changes in specific microRNAs, according to new research, which are associated with the pathological processes of Alzheimer's disease.

Researchers at the Salk Institute found that cannabinol (CBN) and its derivatives could protect brain cells from aging and damage, showing potential for treating neurological disorders like Alzheimer's and traumatic brain injuries. These findings suggest new therapeutic avenues for neurodegeneration.

Individuals who live past 100 with sharp cognitive functions, possess genetic variations that may protect against Alzheimer's. These protective alleles could lead to new Alzheimer’s prevention strategies.

Both alcohol consumption and stress exposure throughout life significantly heighten the risk of developing Alzheimer's disease and other dementias, through mechanisms that likely involve neuroinflammation affecting key brain regions.

A new study has discovered that metabolites from gut bacteria interact with specific human receptors, potentially influencing Alzheimer's disease. These findings could lead to novel therapies targeting these interactions, offering hope for treating or even preventing the disease.

Recent research suggests that not all stressful life events impact Alzheimer's risk equally. Events in childhood and midlife are particularly influential, potentially triggering long-term brain changes and inflammation.

A study suggests a smartphone app could accurately detect mild cognitive impairment, a precursor to Alzheimer's disease, through unsupervised memory tests. This approach could significantly enhance early diagnosis and monitoring of Alzheimer’s, making it more accessible and frequent.

Scientists developed a human neuron model to explore tau protein spread in neurodegenerative diseases, identifying the UFMylation cascade as a novel therapeutic target and uncovering about 500 genes influencing tau propagation.

A new study in Neurology shows erectile dysfunction medications may reduce Alzheimer's risk by 18%. Exploring drug repurposing, researchers found men prescribed these drugs had a lower incidence of Alzheimer's, offering a promising avenue for prevention and highlighting the need...

MIT researchers have found that 40Hz sensory gamma rhythm stimulation can significantly slow Alzheimer's progression by enhancing the brain's glymphatic system to clear amyloid proteins. This breakthrough offers new hope for treating Alzheimer's through non-invasive light and sound therapy.

UCLA Health discovers Kundalini Yoga enhances memory, reverses aging biomarkers, and supports brain health in women at Alzheimer's risk, surpassing standard memory exercises. A holistic approach may offer comprehensive cognitive benefits, highlighting yoga's potential in Alzheimer’s prevention.