LSD

A new randomized controlled study of LSD microdosing has failed to find evidence that the psychedelic practice results in improvements to mood or cognition.

The dopaminergic system appears to play an important but overlooked role in LSD's effects on consciousness, according to new research published in the journal Psychopharmacology. The findings provide new insight into the neurophysiological mechanisms responsible for the unique effects of...

People who report past-year use of the psychedelic drugs LSD (more commonly known as "acid") and salvia divinorum are more likely to report experiencing depression and/or suicidality in the same year, according to new research published in the journal Addictive...

Zebrafish might seem an odd choice in studying human health, but they share 70 per cent of their genes with us and are a popular nonhuman organism used by scientists to study biological processes. They are also incredibly social, making...

A new randomized, double-blind, placebo-controlled study helps to bridge the gap between previous research that had examined LSD as a model of psychosis and research on the therapeutic value of psychedelic drugs. The findings, which appear in the journal Psychological...

Language produced under the influence of the psychedelic drug lysergic acid diethylamide (LSD) displays increased levels of entropy and reduced semantic coherence, according to new research published in the journal Consciousness and Cognition. In other words, people tend to have...

Lysergic acid diethylamide, or LSD, is a drug which produces a variety of cognitive, perceptual and behavioral changes in users. One of these is distortions in interval timing: one’s perception of (relatively) short intervals and, specifically, the ability to reliably...

New research published in Neuropsychopharmacology provides insight into the acute dose dependent effects of LSD. The findings will help in the planning of clinical trials examining the use of the psychedelic drug in patients with psychiatric conditions. Previous research has...

The psychedelic state induced by LSD appears to weaken the association between anatomical brain structure and functional connectivity, according to new research published in the journal NeuroImage. The study also provides evidence that LSD increases the complexity of segregated brain...

MDMA induces only minimal and comparatively weak alterations of consciousness compared with LSD, according to the first controlled study to conduct a head-to-head comparison of the drugs. The findings have been published in the journal Neuropsychopharmacology. "MDMA and LSD are...

New research confirms that the alterations in consciousness associated with very low doses of lysergic acid diethylamide (LSD) are not just the result of a placebo effect. But the findings suggest that these "microdoses" might not have many benefits. Preliminary...

New neuroimaging research provides evidence that the psychedelic drug LSD alters the capacity of the thalamus to control the flow of sensory information to other areas of the brain. The thalamus is a small section of the midbrain through which...

We just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results. We compared people who microdose — that is, who take a psychedelic substance such as LSD (lysergic acid diethylamide) or...

The psychedelic drug LSD induced synesthesia-like experiences in an individual who was born without vision, a condition known as congenital blindness, according to a new case study published in the journal Consciousness and Cognition. Synesthesia occurs when a person experiences...

New research illuminates how the psychedelic drug LSD changes our perception of music. The study found that LSD altered the neural response to music in brain regions associated with auditory processing, memory, emotion, and self-directed thought. "​I have always been...