Alzheimer's Disease

A study in Cell Reports Medicine shows that restoring metabolic balance can reverse advanced Alzheimer’s in mice. These results suggest that the brain can repair itself to achieve full neurological recovery.

New findings suggest cannabis microdosing protects cognition in mild Alzheimer’s cases without the side effects of recreational use.

A new analysis reveals that Alzheimer’s disrupts mitochondrial function and insulin signaling more severely in women than men. The study suggests female brains may attempt unique biological compensations to fight the disease’s progression.

Researchers have preserved memory in mice by triggering support cells to remove amyloid deposits. The findings suggest that enhancing the brain’s natural cleaning system could offer a new therapeutic path for neurodegenerative conditions.

The Alzheimer’s therapy Lecanemab appears to recruit the brain’s immune system. New findings in Nature Neuroscience suggests the drug uses its Fc region to trigger microglia into removing amyloid plaques.

Researchers have found that consuming arginine reduces amyloid beta accumulation in mice and fruit flies. This common amino acid improved behavioral symptoms, pointing to a potential new strategy for managing Alzheimer's pathology.

A new study in rats shows that while high-fat and high-sugar diets both impair memory, only sugar triggers the accumulation of Alzheimer’s-associated proteins within the energy centers of brain cells.

A new study suggests repurposing existing cancer drugs could offer a potent treatment for Alzheimer’s. The combination therapy, tested in mice, works by correcting gene expression errors across both neurons and support cells.

The popular metabolic drug semaglutide failed to preserve memory in patients with early Alzheimer’s disease. New data shows the treatment did not slow cognitive decline compared to a placebo, despite influencing disease-related biology.

A new study suggests that brain communication networks are less stable in individuals with Alzheimer’s. This increased “neural flexibility,” particularly in the visual system, may help predict which individuals will transition to dementia.

Loss of the "push-pull" relationship between the brain's default mode and attention networks is a robust sign of Alzheimer's. New data shows this predicts decline independently of education or protein tangles.

The olfactory system offers a direct pathway to the brain's memory and emotion centers. Now, scientists find this connection may also serve as a crucial diagnostic window into long-term neurological health, preceding traditional clinical symptoms.

A recent paper details a new mechanism for protecting the brain from Alzheimer's-related damage. The research shows how the metabolite NAD+ helps repair cellular function and improve memory.

New research reveals how Alzheimer's disease extends beyond the brain, potentially disrupting the body's energy management system.

A study of dolphins stranded in Florida suggests that repeated exposure to algal toxins may trigger brain changes associated with Alzheimer’s disease.