Dementia

Older adults experiencing both depression and insomnia face an increased risk of developing dementia. However, a recent Journal of Affective Disorders study provides evidence that depressive symptoms are the most consistent indicator of future cognitive decline.

Scientists have discovered an important link between sleep, genetics, and Alzheimer’s disease. New findings suggest that getting poor sleep can accelerate brain shrinkage and memory loss in older adults carrying specific genetic variants.

A high-fat diet and early pesticide exposure affect learning and memory in radically different ways depending on an animal's biological sex and genetic makeup. The findings suggest dietary advice for brain health should be tailored to individual profiles.

The brain relies on a delicate balance of excitatory and inhibitory signals. A new study on mice reveals that excessive inhibitory connections in the prefrontal cortex directly drive the memory loss and cognitive decline associated with aging.

Receiving the live shingles vaccine may help delay cognitive decline in older adults, according to a new study in Alzheimer's & Dementia. The findings provide evidence that the vaccination is associated with a reduced risk of Alzheimer's disease.

Glucosamine is a popular arthritis remedy, but it may be dangerous for those with early memory loss. New research indicates this sugar molecule disrupts brain chemistry, accelerating both Alzheimer's disease progression and mortality rates.

Many patients with Alzheimer’s disease lose their sense of smell before experiencing memory loss. New research reveals how poor communication between specific brain regions causes this sensory decline, offering insights that could lead to earlier diagnostic tests.

While many people with early signs of Alzheimer's disease remain mentally sharp for years, others experience rapid memory loss. Scientists have discovered distinct patterns of decline, which could change how future treatments are tested and developed.

A single snapshot of brain volume forecasts future memory decline better than tracking brain shrinkage over time. This approach highlights the brain's structural reserve, offering a practical tool to identify those at highest risk for developing clinical dementia.

A new study suggests that older adults who consume high amounts of ultra-processed foods face a greater risk of dementia. Switching to fresh, unprocessed foods tends to offer protective benefits for long-term brain health.

Scientists discovered how some people maintain sharp minds despite having Alzheimer's-related brain damage. A recent study identifies a specific genetic signature and introduces a mouse model that recreates this protective state to guide future treatments.

By measuring how well healthy adults track their movements in virtual reality, scientists can estimate future thinning in specific brain regions. This approach could provide a simple, early warning system for neurodegenerative diseases.

New research shows that breathing fine particulate air pollution is associated with a decline in semantic memory among older Black adults. The findings highlight how environmental factors may contribute to racial disparities in dementia.

Why do dementia and depression look so similar in older adults? New research maps the brain's chemistry to show how the two conditions share serotonin disruptions but diverge sharply in how they alter or destroy brain cells.