Dementia

Researchers at the Salk Institute found that cannabinol (CBN) and its derivatives could protect brain cells from aging and damage, showing potential for treating neurological disorders like Alzheimer's and traumatic brain injuries. These findings suggest new therapeutic avenues for neurodegeneration.

Terminal lucidity refers to unexpected, temporary moments of mental clarity and communication in people with severe dementia, often occurring shortly before death. These episodes can involve recalling memories, recognizing loved ones, and conversing meaningfully, despite their progressive cognitive decline.

Individuals who live past 100 with sharp cognitive functions, possess genetic variations that may protect against Alzheimer's. These protective alleles could lead to new Alzheimer’s prevention strategies.

A study involving 8,623 individuals found that reduced visual sensitivity, detectable via eye tests, can predict dementia 12 years before diagnosis.

A new study suggests that a single PET scan measuring amyloid beta levels in the brain can effectively predict the rate of cognitive decline in older adults, potentially streamlining early Alzheimer's diagnosis and management.

A recent study published in Neurology found that older adults without dementia who experienced faster shrinkage of the hippocampus region of the brain also showed quicker cognitive decline, independent of abnormal protein accumulation.

New research finds that individuals with midlife occupations demanding high cognitive engagement have a lower risk of developing mild cognitive impairment and dementia after age 70 compared to those in more routine, less cognitively demanding jobs.

Both alcohol consumption and stress exposure throughout life significantly heighten the risk of developing Alzheimer's disease and other dementias, through mechanisms that likely involve neuroinflammation affecting key brain regions.

A new study has discovered that metabolites from gut bacteria interact with specific human receptors, potentially influencing Alzheimer's disease. These findings could lead to novel therapies targeting these interactions, offering hope for treating or even preventing the disease.

Recent research suggests that not all stressful life events impact Alzheimer's risk equally. Events in childhood and midlife are particularly influential, potentially triggering long-term brain changes and inflammation.

A recent study suggests that higher cognitive abilities in adolescence are linked to a reduced risk of developing dementia 60 years later. Education plays a key role in this relationship, potentially mitigating dementia risks through more complex careers and lifelong...

A study suggests a smartphone app could accurately detect mild cognitive impairment, a precursor to Alzheimer's disease, through unsupervised memory tests. This approach could significantly enhance early diagnosis and monitoring of Alzheimer’s, making it more accessible and frequent.

Scientists developed a human neuron model to explore tau protein spread in neurodegenerative diseases, identifying the UFMylation cascade as a novel therapeutic target and uncovering about 500 genes influencing tau propagation.

A UK study found individuals with behavioral variant frontotemporal dementia who had musical experience showed better social and emotional functioning. This suggests that music might play a role in enhancing socio-emotional well-being in dementia patients.

Researchers found that brains have grown larger over recent decades, with those born in the 1970s having significantly bigger brain volumes and surface areas compared to those born in the 1930s.