Scientists developed a human neuron model to explore tau protein spread in neurodegenerative diseases, identifying the UFMylation cascade as a novel therapeutic target and uncovering about 500 genes influencing tau propagation.
A UK study found individuals with behavioral variant frontotemporal dementia who had musical experience showed better social and emotional functioning. This suggests that music might play a role in enhancing socio-emotional well-being in dementia patients.
Individuals with depression and concurrent depersonalization/derealization symptoms experience a more severe illness course, face greater challenges in treatment response, and endure poorer overall health outcomes compared to those with depression alone.
Loneliness is linked to addictive smartphone use among adolescents, with self-esteem and boredom proneness serving as partial mediators, according to a recent study.
A recent study identified altered brain pH and lactate levels as common metabolic dysfunctions across various neuropsychiatric disorders, linking these changes to cognitive impairment and suggesting a unified pathway in the pathophysiology of these conditions.
A recent study found that stress accelerates biological aging in midlife, comparable to smoking and low socioeconomic status, confirming a common belief through four stress measures.
Researchers found that brains have grown larger over recent decades, with those born in the 1970s having significantly bigger brain volumes and surface areas compared to those born in the 1930s.
Recent research suggests self-objectification plays a role in the sexual pleasure gap, revealing an association between self-viewing through an external lens and sexual dysfunction in women.
A recent study found that individuals with more severe ADHD symptoms outperformed others in an online foraging task, demonstrating a greater propensity for exploration and higher reward collection, suggesting an adaptive advantage of ADHD traits in certain environments.
New research in The BMJ involving over 14,000 participants finds that walking, jogging, yoga, and strength training moderately reduce depression symptoms. Exercise intensity correlates with greater benefits, highlighting physical activity as a valuable, underused treatment for depression.
Mild cognitive impairment – an early stage of dementia – is widely underdiagnosed in people 65 and older.
Neuroimaging research has found individuals with social anxiety disorder have increased cortical thickness in specific brain regions, indicating altered brain structures linked to attention and socio-emotional processing, compared to healthy individuals.
A 61-year-old woman experienced a severe headache during sexual activity, leading to the discovery of a life-threatening brain hemorrhage. Despite no identifiable cause, she fully recovered after treatment.
Research suggests specific strains of probiotics, like certain Lactobacillus species, can enhance mood by modulating stress responses. Experiments in mice show that transferring microbiota from stressed to "clean" mice induces stress behaviors, highlighting the gut-brain axis's role in emotional health.
A decade-long U.S. study found a slight increase in dementia risk among people exposed to PM2.5 air pollution, particularly from agriculture and wildfires. The research emphasizes the need for targeted air quality interventions to reduce dementia's burden.