A new study suggests that the use of certain antidepressants, specifically SSRIs and SNRIs, may weaken the acute subjective effects of psilocybin in some individuals. The findings, which appear in the Journal of Psychopharmacology, indicate that this dampening effect on...
Blocking the subjective psychedelic effects of psilocybin does not appear to interfere with the substance's ability to potentially help with obsessive behaviors, according to new research published in Translational Psychiatry. The findings contribute to the growing body of research on...
A new study has found that classic psychedelic use is associated with increased psychological distress among unemployed individuals, according to new research published in the Journal of Psychedelic Studies.
A new study has found that naturalistic psychedelic use is associated with specific psychological strengths, suggesting that psychedelics can have positive effects on mental well-being compared to other substances like cannabis and alcohol. The findings, published in the International Journal...
A study published in Neuropsychopharmacology provides new insight into how the psychedelic drug LSD influences the way different brain regions communicate. The findings suggest that LSD disrupts the brain's gatekeeping process, leading to increased information flow and altered perception.
The psychedelic substances 5-MeO-DMT causes a long-lasting increase in the number of tiny protrusions called dendritic spines in the brain, according to new research published in Neuropsychopharmacology. The study, which was conducted on mice, sheds light on the behavioral and...
New research published in iScience provides unique insights into how psilocybin alters brain activity during psychedelic experiences. The findings suggest that while the overall activity of the brain becomes more chaotic during the psychedelic state, the brain's ability to maintain...
Scientists have identified specific patterns of brain network reconfigurations that occur when people take both classical and non-classical psychedelic drugs. Their findings, published in NeuroImage, shed new light on how psychedelics affect the brain and consciousness.
Scientists are interested in studying psychedelic substances because they have the potential to alter perception, cognition, and mood in ways that may be beneficial for treating a variety of mental health conditions. Some studies suggest that certain psychedelics may have...
Patients tend to have a stronger brain response to music the day after receiving psilocybin-assisted therapy, according to new research published in the Journal of Affective Disorders. The stronger response to music was related to how intense the psychedelic experience...
People who use psychedelic drugs for entheogenic purposes tend to also have heightened spiritual development, according to new research published in the Journal of Psychedelic Studies. The new findings provide insight into how entheogenic drug use is related to spirituality...
The psychedelic drug lysergic acid diethylamide (LSD) make people learn faster when receiving feedback and enhances exploratory behavior, according to new research published in Psychological Medicine. The findings could help shed light on the underlying cognitive mechanisms behind the potential...
It is widely known that doing drugs can cause neurological impairments, but it can be difficult to know why. A study published in NeuroImage: Clinical provides evidence that chronic MDMA may not cause white matter lesions that are seen from...
People who use psychedelic substances in an attempt to self-treat their mental health tend to report mild-to-moderate positive outcomes, according to new research published in the Journal of Psychopharmacology. But there were more negative effects reported by these individuals than...
In people with advanced cancer, psychedelic drugs like psilocybin, LSD and MDMA may significantly reduce the severity of depression and anxiety symptoms. Psychedelic sessions might have an advantage over traditional prescription antidepressants for patients with cancer-related depression or anxiety because...