Alzheimer's Disease

In a study using an Alzheimer’s disease mouse model, researchers found that cannabidiol reduced memory loss and brain abnormalities. The compound worked by enhancing the function of glycine receptors, which help regulate neuronal activity in the brain's memory center.

A groundbreaking genome-wide analysis has revealed new genetic regions associated with Alzheimer’s disease—many missed in past studies focused on European populations. The findings point to underexplored biological pathways and highlight the value of studying diverse ancestry groups.

A low-cost, noninvasive eye scan could help detect Alzheimer’s disease earlier than current methods. The technique may expand access to early diagnosis, especially in underserved communities, and provide a valuable tool for intervention before irreversible brain damage occurs.

A recent review published in Cureus explores the relationship between caffeine and Alzheimer’s disease. The findings suggest that higher caffeine intake may reduce the risk of cognitive decline, especially in people with early symptoms of memory impairment.

A study using magnetoencephalography found that Alzheimer’s patients show increased high-frequency brain oscillations, even without epileptic activity. These waveforms may offer a new biomarker for hyperexcitability and help identify those who could benefit from targeted seizure treatments.

New research reveals that mutations in three genes linked to familial Alzheimer’s can predict when symptoms begin, acting like molecular clocks. The study may help improve diagnosis and inform targeted therapies for early-onset forms of the disease.

A novel vaccine targeting a toxic form of tau protein reduced brain atrophy and improved memory in mice and monkeys. The study offers a potentially safer, longer-lasting, and more cost-effective approach than current antibody-based Alzheimer’s treatments.

A study in fruit flies suggests that impaired glucose metabolism in glial cells contributes to neurodegeneration in Alzheimer’s. Enhancing glucose transport in these cells reduced inflammation and preserved neurons, highlighting a new potential angle for therapeutic intervention.

A surprising discovery in spider brains has led scientists to uncover a hidden waste removal system in the human brain. Its breakdown may explain the progressive neuron loss seen in Alzheimer’s disease, offering a new target for early intervention.

Researchers have found that a cognitive flexibility task, combined with brain scans and blood tests, can reveal early Alzheimer’s risk in older African American adults who appear cognitively healthy.

Semaglutide, the active ingredient in Ozempic, may help fight Alzheimer’s. Researchers found it reduces brain inflammation and improves memory in mice with Alzheimer’s-like symptoms.

A natural compound from rosemary and sage, in a new stable form, improved Alzheimer's-like symptoms in mice, suggesting a plant-based therapy.

Scientists found that air pollutants trigger a chemical change (S-nitrosylation) in a vital brain protein (CRTC1), disrupting memory-related gene activity. Blocking this process partially restored memory in Alzheimer’s mice and could lead to new treatments.

Using a new brain mapping method, researchers found that specific memory cells in the hippocampus are highly susceptible to protein buildup linked to Alzheimer's disease, while other brain cells are more resistant.

After the start of a buildup of a protein called amyloid-β in the brain, men experience faster increases in certain blood markers of brain changes, more rapid brain shrinkage, and quicker declines in thinking skills compared to women