An analysis of the UK Biobank data revealed a J-shaped relationship between coffee consumption and the risk of depression and anxiety. Individuals who consumed 2-3 cups of coffee daily had the lowest risk of these mental disorders. However, risks increased...
A recent study in ACS Pharmacology & Translational Science discovered that a temporary spike in stress hormones, specifically corticosterone, plays a central role in reducing anxiety-like behaviors in mice given the psychedelic substance psilocybin. The findings offer crucial insights into...
New research published in the journal Communication Biology shows that psychedelic substances like LSD and ketamine induce "hypersynchrony" in the brain, characterized by highly synchronized high-frequency oscillations across different regions. This unique synchronization, observed in rats, provides insights into altered...
Researchers have found that compounds from the lion's mane mushroom, particularly hericene A, promote nerve cell growth, increase the production of brain-boosting molecules called neurotrophins, and improve memory performance in mice, suggesting their potential as cognitive enhancers. Their findings have...
A recent case study published in Frontiers in Psychology compared the experiences of a near-death experience (NDE) and an experience induced by the psychedelic drug 5-MeO-DMT in a 54-year-old man. While the study found notable similarities such as ego dissolution...
A new study published in the Journal of Psychopharmacology suggests that regular cannabis use alters the connectivity of the executive control network in the brain, a network involved in attention and high-level task performance. Surprisingly, these alterations were found to...
Researchers from Michigan State University's Sleep and Learning Lab have found that while caffeine may help maintain attention in sleep-deprived individuals, it does not reduce errors in complex tasks requiring placekeeping. The study also revealed that napping during an overnight...
Researchers in the United Kingdom recently conducted a study to determine if psychedelic-assisted psychotherapy could be a more cost-effective option than more traditional forms of psychotherapy for those who experience depression. The results suggested that this unique approach could be...
A new study found that giving mice 5-MeO-DMT, a short-acting psychedelic, leads to a long-lasting increase of dendritic spine density in the medial frontal cortex region of their brains, potentially countering the neural changes produced by depression. The psychological effects...
New research published in Lancet Public Health reveals that individuals who have experienced higher numbers of adverse childhood experiences are more likely to develop persistent and regular cannabis use patterns during adolescence. The study underscores the crucial link between childhood...
Ketamine tends to increase early life stress-induced aggression in rodent models, but it does not induce significant effects on other behavioral measures related to mood disorders, such as fear memory, anxiety-like behavior, and depression-like behavior, according to new research published...
A recent study published in Frontiers in Psychology explores the potential positive impact of mindfulness meditation and psychedelic use on leadership development among business managers. The research highlights how both practices contribute to enhanced well-being, awareness, creativity, and interpersonal attitudes.
A study conducted using data from the 2020 National Survey on Drug Use and Health has found that individuals reporting serious psychological distress are more likely to be users of cannabis. Both moderate and serious levels of psychological distress were...
Mike Jay's "Psychonauts: Drugs and the Making of the Modern Mind" investigates the history and influence of psychoactive substances, shedding light on how the human relationship with these substances has evolved over time. With a particular focus on the impact...
Cannabis-based medicinal products might help to improve symptom severity, sleep quality, and health-related quality of life in those with anxiety, according to new research published in the journal Psychopharmacology. The findings highlight the need for further research, including randomized controlled...